Table 1 |
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Demographic data and characteristics of critically ill patients, classified according to their rate of gastric emptying |
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Normal GE (n = 14) |
Delayed GE (n = 25) |
P value |
|
|
|
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Age, years |
57.5 ± 3.8 |
56.3 ± 2.8 |
0.87 |
|
Gender, male/female |
7/7 |
17/8 |
0.41 |
|
Body mass index, kg/m2 |
28.3 ± 1.3 |
27.7 ± 1.2 |
0.78 |
|
APACHE II score on study day |
22.6 ± 1.1 |
22.1 ± 1.0 |
0.86 |
|
Serum creatinine, mmol/L |
0.08 ± 0.01 |
0.11 ± 0.02 |
0.14 |
|
Baseline blood glucose, mmol/L |
7.1 ± 0.2 |
7.1 ± 0.2 |
0.99 |
|
Admission diagnosisa, percentage (number) |
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Sepsis |
36% (5) |
19% (5) |
0.28 |
|
Respiratory failure |
43% (6) |
15% (4) |
0.13 |
|
Multi-trauma |
21% (3) |
32% (8) |
0.48 |
|
Head injuryb |
21% (3) |
34% (9) |
0.48 |
|
Aortic dissection |
7% (1) |
8% (2) |
0.99 |
|
Pancreatitis |
0% (0) |
4% (1) |
0.99 |
|
Retroperitoneal bleed |
7% (1) |
0% (0) |
0.35 |
|
Medication, percentage (number) |
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Morphine ± midazolam |
57% (8) |
68% (17) |
0.44 |
|
Propofol |
43% (6) |
31% (8) |
0.44 |
|
Inotropes (adrenaline/noradrenalin) |
57% (8) |
46% (12) |
0.51 |
|
Plasma CCK concentration, pmol/L |
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Fasting |
6.1 ± 0.4 |
8.5 ± 1.0 |
0.045 |
|
Postprandial |
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At 60 minutes |
8.2 ± 0.7 |
10.1 ± 0.8 |
0.03 |
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At 120 minutes |
7.1 ± 0.7 |
9.8 ± 0.8 |
0.03 |
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Plasma PYY concentration, pmol/L |
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Fasting |
15.6 ± 1.3 |
22.8 ± 2.2 |
0.03 |
|
Postprandial |
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At 60 minutes |
21.0 ± 1.8 |
25.0 ± 2.2 |
0.02 |
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At 120 minutes |
18.9 ± 1.9 |
24.9 ± 2.0 |
0.02 |
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Data are mean ± standard error of the mean. aOne patient may have one or more admission diagnoses. bIncluding sub-arachnoid haemorrhage and massive cerebral ischemic event. APACHE II, Acute Physiology and Chronic Health Evaluation II; CCK, cholecystokinin; GE, gastric emptying; PYY, peptide YY. |
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Nguyen et al. Critical Care 2007 11:R132 doi:10.1186/cc6205 |
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