Brain dysfunction in sepsis: what can we learn from cerebral perfusion studies?
Department of Anaesthesia, University Hospital Basel, Spitalstrasse 21, CH-4031 Basel, Switzerland
Critical Care 2008, 12:107 doi:10.1186/cc6217
See related research by Thees et al., http://ccforum.com/content/11/6/R123Published: 18 January 2008
Investigations on the relationship between sepsis, brain dysfunction, and cerebral perfusion are methodologically very difficult to perform. It is important to interpret the results of such studies in view of our limited ability to diagnose and quantify brain dysfunction and to consider our limited understanding of the mechanisms that lead to or are associated with brain dysfunction in sepsis.