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Commentary

Effect of sepsis therapies on health-related quality of life

Sara E Erickson and Greg S Martin*

Author Affiliations

Division of Pulmonary, Allergy and Critical Care, Emory University School of Medicine, Grady Memorial Hospital, 49 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA

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Critical Care 2008, 12:109 doi:10.1186/cc6215

Published: 22 January 2008

Abstract

Sepsis is one of the most common conditions encountered in the intensive care unit and is the 10th leading cause of death overall in the United States. Both long-term survival and health-related quality of life are reduced in survivors of sepsis, yet there is little knowledge of the effect of sepsis-specific interventions on either long-term survival or health-related quality of life. The present article discusses the importance of studying health-related quality of life as it relates to sepsis management strategies, particularly in the context of pharmacologic therapy with recombinant human activated protein C.