Critical Care

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Intensive insulin therapy and mortality in critically ill patients

Miriam M Treggiari, Veena Karir, N David Yanez, Noel S Weiss, Stephen Daniel and Steven A Deem*

Critical Care 2008, 12:R29 doi:10.1186/cc6807

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Tight glycemic control: what do we really know, and what should we expect?

Stanley A Nasraway, Rishi Rattan Critical Care 2010, 14:198 (24 September 2010)

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Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury

Roman Meierhans, Markus Béchir, Silke Ludwig, Jutta Sommerfeld, Giovanna Brandi, Christoph Haberthür, Reto Stocker, John F Stover Critical Care 2010, 14:R13 (8 February 2010)

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Health technology assessment review: Computerized glucose regulation in the intensive care unit - how to create artificial control

Miriam Hoekstra, Mathijs Vogelzang, Evgeny Verbitskiy, Maarten WN Nijsten Critical Care 2009, 13:223 (16 October 2009)

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The impact of early hypoglycemia and blood glucose variability on outcome in critical illness

Sean M Bagshaw, Rinaldo Bellomo, Michael J Jacka, Moritoki Egi, Graeme K Hart, Carol George, Critical Care 2009, 13:R91 (17 June 2009)

Early hypoglycemia and blood glucose variability show a clinically relevant association with increased mortality in critically ill patients, while the severity of hypoglycemia in particular corresponds closely to the extent of this increase.