Table 3

Serial BNP measurements by edema classification

Period

Direction of BNP change

n (ΔBNP, pg/ml)

P


ALI/ARDS

CHF


Days 1 to 2

Increase

17 (254 ± 302)

5 (228 ± 287)

Decrease

9 (-246 ± 178)

8 (-252 ± 208)

0.17b

Alla

26 (73 ± 339)

17 (-52 ± 290)

0.21c

Days 2 to 3

Increase

9 (143 ± 200)

5 (396 ± 132)

Decrease

11 (-191 ± 187)

7 (-160 ± 142)

1.0b

Alla

24 (-34 ± 231)

15 (57 ± 281)

0.28c


BNP, B-type natriuretic peptide; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; CHF, congestive heart failure. The table shows an analysis of changes in BNP levels in direction (increase or decrease) and magnitude (ΔBNP) from day 1 to day 2 and from day 2 to day 3, classified by edema type. Where errors are shown, results are means ± SD.

aValues for some patients remained above the upper limit of the assay (1,300 pg/ml) and were consider unchanged. bχ2 comparing the proportion of subjects with an increase in BNP by edema type; ct test of magnitude of BNP change by edema type.

Levitt et al. Critical Care 2008 12:R3   doi:10.1186/cc6764

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