Figure 1.

Relative risk (RR) and 95% confidence interval (CI) for five studies of intensive insulin therapy (IIT). The calculation of RR is based on the latest reported mortality: 90-day mortality for Van den Berghe and colleagues' medical intensive care unit (MICU) study and the Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP) study; hospital mortality for Van den Berghe and colleagues' surgical ICU (SICU) study; and ICU mortality for the GLUCONTROL study and Arabi and colleagues' study [49].