Table 2

Measurements of mean BP and AWP (30 and 60 minutes)

Time

Start of experiment

End of experiment

Mean BP (mmHg)

LVT-30

103.8 ± 1.4

87.6 ± 4.0

LVT-60

105.3 ± 2.3

75.3 ± 5.2^‡

HVT-30

103.8 ± 1.4

93 ± 5.1

HVT-60

105.3 ± 1

88 ± 4.6

HVT+dopamine-30

106.3 ± 1.7

92.3 ± 2.8

HVT+dopamine-60

106.5 ± 2.5

97.5 ± 3.8^†

AWP (mmHg)

LVT-30

14.8 ± 1.1*

16.6 ± 1.1*

LVT-60

13.9 ± 1.2*

18.3 ± 0.8*

HVT-30

30 ± 1.7

28.8 ± 1.4

HVT-60

31 ± 1.8

28 ± 1.6

HVT+dopamine-30

24.6 ± 0.6

23 ± 0.9⁺

HVT+dopamine-60

27.5 ± 1.9

26.5 ± 1.3

Ten animals were included in each group. Values are expressed as means ± standard error of the mean. *Statistically significant difference for the comparison of the LVT-30 group with HVT-30 and HVT+DA-30 groups, and of the LVT-60 group with HVT-60 and HVT+DA-60 groups (P = 0.001) at the beginning and end of the experiment. ⁺Statistically significant difference between HVT-30 and HVT+DA-30 groups (P = 0.012) at the end of the experiment. ^†Statistically significant difference between LVT-60 and HVT+DA-60 groups (P = 0.018) at the end of the experiment. ^‡Statistically significant difference between LVT-30 and LVT-60 groups (P = 0.025) at the end of experiment. AWP, airway pressure; BP, blood pressure; HVT-30, high tidal volume for 30 minutes; HVT-60, high tidal volume for 60 minutes; HVT+dopamine-30, high tidal volume plus dopamine for 30 minutes; HVT+dopamine-60, high tidal volume plus dopamine for 60 minutes; LVT-30, low tidal volume for 30 minutes; LVT-60, low tidal volume for 60 minutes.

Chamorro-Marín et al. Critical Care 2008 12:R39   doi:10.1186/cc6829