Table 4

Comparison of statistical significance for patient risk variables between survivors and non-survivors

Survivors

Non-survivors

P value

SPRINT cohort

n = 310

n = 61

Average BG, mmol/L

6.1 (5.6–6.6)

5.9 (5.5–6.5)

0.55^a

Maximum BG, mmol/L

9.9 (8.6–11.8)

10.4 (8.5–12.1)

0.62^a

BG range, mmol/L

6.1 (4.7–8.1)

6.5 (5.0–8.8)

0.35^a

APACHE II score

18.0 (14.0–22.0)

25.0 (18.0–30.3)

<0.01^a

APACHE II risk of death

23% (12%-41%)

50% (26%-71%)

<0.01^a

Average percentage goal feed

48% (0%-71%)

54% (29%-68%)

0.42^a

Average hourly insulin, U/hour

2.7 (2.2–3.3)

2.5 (2.1–3.2)

0.65^a

Diabetic history

56 (18.1%)

6 (9.8%)

0.12^b

Retrospective cohort

n = 336

n = 77

Average BG, mmol/L

7.5 (6.6–8.4)

7.3 (6.6–8.3)

0.83^a

Maximum BG, mmol/L

10.5 (9.4–12.6)

11.3 (10.0–13.6)

0.04^a

BG range, mmol/L

5.8 (3.8–8.6)

6.8 (4.7–9.5)

0.05^a

APACHE II score

18.0 (15.0–22.0)

24.0 (18.8–29.0)

<0.01^a

APACHE II risk of death

25% (13%-43%)

51% (23%-67%)

<0.01^a

Average hourly insulin, U/hour

0.8 (0.0–1.7)

1.0 (0.5–1.5)

0.33^a

Diabetic history

58 (17.3%)

13 (16.9%)

0.94^b

Statistical significance was tested for average, maximum and range of blood glucose, APACHE II score, average feed rate, and diabetic history between SPRINT intensive care unit survivors and mortalities. Data are expressed as number (percentage) or per-patient median (interquartile range) where appropriate. ^aMann-Whitney U test; ^bchi-square test. APACHE, Acute Physiology And Chronic Health Evaluation; BG, blood glucose concentration; SPRINT, Specialised Relative Insulin Nutrition Tables.

Chase et al. Critical Care 2008 12:R49   doi:10.1186/cc6868