Table 3 |
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|
Summary of main pharmacokinetic results |
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|
Tmax, hours |
Cmax, pg/mL |
AUC(0–24), ng-hours/L |
Overall t1/2, hours |
Oral clearance (Cl/F), L/hour |
C(08), pg/mL |
|
|
|||||
|
0.5 (0) |
14,974 (3,200) |
29,979 (8,205) |
1.47 (0.28) |
351.0 (96.7) |
84 (64) |
|
|
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|
Data are presented as mean (standard deviation). AUC(0–24), area under the concentration time curve between time 0 and 24 hours; C(08), plasma concentration at 8 a.m.; Cl/F, clearance/bioavailability (oral dose/area under the zero moment curve); Cmax, maximum plasma concentration; t1/2, plasma half-life; Tmax. |
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|
Bourne et al. Critical Care 2008 12:R52 doi:10.1186/cc6871 |
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