|
Mean arterial pressure and heart rate |
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| PEG-albumin |
HES |
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|
|
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| MAP |
HR |
MAP |
HR |
|
|
|
||||
| HD |
96.6 ± 5.6 |
482.4 ± 28.8 |
100.0 ± 8.3 |
493.8 ± 20.9 |
| H0 |
56.8 ± 7.2*†b |
396.8 ± 65.0*† |
43.0 ± 10.7*† |
305.3 ± 83.5*† |
| H30 |
43.0 ± 7.6*†b |
342.8 ± 54.0*† |
33.3 ± 6.7*† |
376.8 ± 98.8*† |
| H60 |
42.6 ± 10.3*† |
367.2 ± 34.6*† |
- |
- |
| S30 |
46.0 ± 10.2*† |
338.2 ± 18.5*† |
- |
- |
| S60 |
46.0 ± 11.9*† |
325.8 ± 21.0*† |
- |
- |
|
Shown are the changes in MAP and HR between the two study groups at different time points. Baseline: MAP (mmHg) = 107.4 ± 8.2, HR (beats/minute) = 466.3 ± 24.2. Within the same treatment group: *versus baseline; †versus hemodilution. Among treatments: PEG-albumin versus bHES. HD, hemodilution; H0, beginning of hemorrhage; H30, midpoint in the hemorrhage period when most of the 60% volume has been withdrawn; H60, end of the hemorrhage period; HES, hydroxyethyl starch; HR, heart rate; MAP, mean arterial pressure; PEG-albumin, polyethylene glycol-conjugated human serum albumin; S30, 30 minutes after beginning of shock; S60, end of the experiment. | ||||
Martini et al. Critical Care 2008 12:R54 doi:10.1186/cc6874 |
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