Table 2

Diagnostic performance of the eosinophil count and the C-reactive protein level in the prediction of sepsis on intensive care unit admission

Variable

Noninfection versus infection

SIRS versus infection


C-reactive protein level

Eosinophil cell count

C-reactive protein level

Eosinophil cell count


Cutoff value

>70 mg/l

<50 cells/mm3

>80 mg/l

<40 cells/mm3

Sensitivity (%)

68 (59 to 76)

80 (71 to 86)

68 (59 to 79)

80 (71 to 86)

Specificity (%)

61 (47 to 74)

91 (79 to 96)

55 (32 to 76)

80 (55 to 93)

Positive likelihood ratio

1.77 (1.25 to 2.51)

9.12 (3.9 to 21)

1.52 (0.92 to 2.50)

4.00 (1.65 to 9.65)

Negative likelihood ratio

0.52 (0.39 to 0.69)

0.21 (0.15 to 0.31)

0.57 (0.41 to 0.81)

0.25 (0.17 to 0.36)

Area under the receiver operating characteristic curve

0.77 (0.70 to 0.84)

0.89 (0.83 to 0.94)

0.77 (0.67 to 0.87)

0.84 (0.74 to 0.94)


Data in parentheses are 95% confidence intervals. Noninfection, negative + systemic inflammatory response syndrome (SIRS); infection, sepsis + severe sepsis + septic shock.

Abidi et al. Critical Care 2008 12:R59   doi:10.1186/cc6883

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