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Antifungal prophylaxis in critically ill patients

Luciano Silvestri1*, Durk F Zandstra2, Hendrick KF van Saene3, Andy J Petros4, Sujatha Thyagarajan5, Miguel A de la Cal6 and Corrado Thomann1

Author Affiliations

1 Department of Emergency, Unit of Anaesthesia and Intensive Care, Presidio Ospedaliero, Via Vittorio Veneto 171, 34170 Gorizia, Italy

2 Department of Intensive Care, Onze Lieve Vrouwe Gasthuis, Oosterpark 9, 1091 AC Amsterdam, The Netherlands

3 Department of Medical Microbiology, University of Liverpool, Duncan Building, Daulby Street, Liverpool L69 3GA, UK

4 Paediatric and Neonatal Intensive Care Unit, Great Ormond Street Children's Hospital, Great Ormond Street, London WC1N 3JH, UK

5 Department of Intensive Care, Alder Hey Children's Hospital, Eaton Road, Liverpool L12 2AP, UK

6 Intensive Care Unit, University Hospital, Carretera de Toledo km 12,500, 28905 Getafe, Madrid, Spain

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Critical Care 2008, 12:420 doi:10.1186/cc6906

Published: 13 June 2008

First paragraph (this article has no abstract)

We congratulate van Till and colleagues on their review showing that selective decontamination of the digestive tract (SDD) is more effective than single-drug prophylaxis (SAP) in reducing yeast colonisation, infection and mortality [1].