|
Patient characteristics at intensive care unit admission |
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| Intention to treat |
Modified intention to treat |
|||||
| Antibiotic treatment n = 22 |
No antibiotic treatment n = 36 |
P value |
Antibiotic treatment n = 18 |
No antibiotic treatment n = 26 |
P value |
|
|
|
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| Age, years |
62 ± 15 |
67 ± 12 |
0.194 |
61 ± 15 |
67 ± 12 |
0.321 |
| Male gender |
15 (68) |
24 (66) |
>0.999 |
13 (72) |
16 (61) |
0.531 |
| SAPS II |
47 ± 14 |
47 ± 18 |
0.994 |
45 ± 17 |
48 ± 15 |
0.481 |
| LOD score |
6.6 ± 3.5 |
6.2 ± 3.6 |
0.711 |
6.5 ± 3.8 |
6.4 ± 3.9 |
0.990 |
| McCabe |
0.687 |
0.625 |
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| Nonfatal underlying disease |
10 (45) |
14 (38) |
10 (55) |
11 (42) |
||
| Ultimately fatal underlying disease |
9 (40) |
17 (47) |
7 (38) |
12 (46) |
||
| Rapidly fatal underlying disease |
3 (13) |
5 (13) |
1 (5) |
3 (11) |
||
| Admission category |
>0.999 |
0.409 |
||||
| Medical |
19 (86) |
30 (83) |
15 (83) |
21 (80) |
||
| Surgical |
3 (13) |
5 (13) |
3 (16) |
4 (15) |
||
| Trauma |
0 (0) |
1 (2) |
0 (0) |
1 (3) |
||
| Comorbidities |
||||||
| COPD |
9 (40) |
17 (47) |
0.787 |
7 (38) |
12 (46) |
0.760 |
| Cardiac failure |
6 (27) |
4 (11) |
0.156 |
6 (33) |
3 (11) |
0.128 |
| Cirrhosis |
0 (0) |
3 (8) |
0.281 |
0 (0) |
3 (11) |
0.258 |
| Chronic dialysis |
4 (18) |
2 (5) |
0.187 |
3 (16) |
1 (3) |
0.289 |
| Diabetes mellitus |
6 (27) |
3 (8) |
0.070 |
5 (27) |
3 (11) |
0.204 |
| Transfer from other wards |
12 (54) |
12 (33) |
0.285 |
9 (50) |
9 (34) |
0.361 |
| Prior antibiotic treatment |
9 (40) |
12 (33) |
0.585 |
8 (44) |
8 (30) |
0.525 |
| Infection at ICU admission |
18 (81) |
25 (69) |
0.365 |
14 (77) |
20 (76) |
>0.999 |
| Cause for ICU admission |
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| Community-acquired pneumonia |
6 (27) |
10 (27) |
>0.999 |
6 (33) |
6 (23) |
0.506 |
| Acute exacerbation of COPD |
3 (13) |
14 (38) |
0.073 |
3 (16) |
9 (34) |
0.303 |
| Congestive heart failure |
3 (13) |
1 (2) |
0.319 |
3 (16) |
1 (3) |
0.289 |
| Neurologic failure |
2 (9) |
5 (13) |
0.698 |
1 (5) |
4 (15) |
0.634 |
| Acute poisoning |
2 (9) |
2 (5) |
0.681 |
2 (11) |
2 (7) |
>0.999 |
| Others |
6 (27) |
4 (11) |
0.156 |
3 (16) |
4 (15) |
>0.999 |
|
Results of univariate analysis are presented. Data are expressed as frequency (percentage) or mean ± standard deviation. COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; LOD, logistic organ dysfunction; SAPS, Simplified Acute Physiology Score. | ||||||
Nseir et al. Critical Care 2008 12:R62 doi:10.1186/cc6890 |
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