|
Patient characteristics at the day of random assignment |
||||||
| Intention to treat |
Modified intention to treat |
|||||
| Antibiotic treatment n = 22 |
No antibiotic treatment n = 36 |
P value |
Antibiotic treatment n = 18 |
No antibiotic treatment n = 26 |
P value |
|
|
|
||||||
| Duration of mechanical ventilation before random assignment, days |
17 ± 9 |
13 ± 6 |
0.232 |
17 ± 10 |
12 ± 6 |
0.113 |
| SAPS II |
33 ± 13 |
36 ± 13 |
0.195 |
32 ± 10 |
36 ± 12 |
0.120 |
| LOD score |
4.1 ± 2 |
4.9 ± 2.4 |
0.185 |
3.8 ± 1.5 |
4.8 ± 2.6 |
0.210 |
| Temperature, °C |
38.1 ± 0.6 |
38.3 ± 0.6 |
0.408 |
38.2 ± 0.5 |
38.2 ± 0.4 |
0.402 |
| Leucocytes, × 109 cells/L |
12 ± 5.9 |
12 ± 6 |
0.619 |
11.2 ± 4.2 |
11.9 ± 5.7 |
0.775 |
| C-reactive protein, mg/mL |
111 ± 61 |
104 ± 80 |
0.417 |
104 ± 50 |
95 ± 67 |
0.295 |
| Procalcitonin, ng/mL, median (IR) |
0.6 (0.10–3.1) |
0.8 (0.5–2.7) |
0.282 |
0.7 (0.05–2.8) |
0.83 (0.36–2.1) |
0.494 |
|
Results of univariate analysis are presented. Data are expressed as mean ± standard deviation unless otherwise indicated. IR, interquartile range; LOD, logistic organ dysfunction; SAPS, Simplified Acute Physiology Score. | ||||||
Nseir et al. Critical Care 2008 12:R62 doi:10.1186/cc6890 |
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