|
Bacteria associated with ventilator-associated tracheobronchitis episodes |
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| Intention to treat |
Modified intention to treat |
|||
| Antibiotic treatment n = 22 |
No antibiotic treatment n = 36 |
Antibiotic treatment n = 18 |
No antibiotic treatment n = 26 |
|
|
|
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| Microorganisms, number |
27 |
39 |
22 |
29 |
| Polymicrobial VAT |
5 (22) |
3 (8) |
4 (22) |
3 (11) |
| MDR bacteria |
10 (45) |
17 (47) |
9 (50) |
14 (53) |
| Gram-negative |
20 (90) |
27 (75) |
16 (88) |
20 (76) |
| Pseudomonas aeruginosa |
8 (36) |
11 (30) |
7 (31) |
9 (34) |
| Enterobacter species |
2 (9) |
3 (8) |
2 (11) |
3 (11) |
| Escherichia coli |
3 (13) |
3 (8) |
1 (5) |
2 (7) |
| Proteus mirabilis |
3 (13) |
1 (2) |
2 (11) |
1 (3) |
| Citrobacter freundii |
1 (4) |
2 (5) |
1 (5) |
1 (3) |
| Acinetobacter baumannii |
0 (0) |
2 (5) |
0 (0) |
2 (7) |
| Morganella morgani |
1 (4) |
2 (5) |
1 (5) |
1 (3) |
| Hemophilus influenzae |
0 (0) |
1 (2) |
0 (0) |
1 (3) |
| Stenotrophomonas maltophilia |
1 (4) |
1 (2) |
1 (5) |
0 (0) |
| Klebsiella oxytoca |
1 (4) |
1 (2) |
1 (5) |
0 (0) |
| Gram-positive |
7 (31) |
12 (33) |
6 (33) |
9 (34) |
| Methicillin-resistant Staphylococcus aureus |
3 (13) |
6 (16) |
3 (16) |
5 (19) |
| Methicillin-sensitive S. aureus |
3 (13) |
4 (11) |
2 (11) |
4 (15) |
| Streptococcus pneumoniae |
1 (4) |
2 (5) |
1 (5) |
0 (0) |
|
P > 0.2 for all comparisons (antibiotic versus no antibiotic treatment). Results are presented as number (percentage) unless otherwise indicated. MDR, multidrug-resistant; VAT, ventilator-associated tracheobronchitis. | ||||
Nseir et al. Critical Care 2008 12:R62 doi:10.1186/cc6890 |
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