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Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients

Marjolein de Wit*, Chris Gennings, Wendy I Jenvey and Scott K Epstein

Critical Care 2008, 12:R70 doi:10.1186/cc6908

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Remifentanil discontinuation and subsequent intensive care unit-acquired infection: a cohort study

Saad Nseir, Jérémy Hoel, Guillaume Grailles, Aude Soury-Lavergne, Christophe Di Pompeo, Daniel Mathieu, Alain Durocher Critical Care 2009, 13:R60 (21 April 2009)

Abstract | Full text | PDF | PubMed | Editor’s summary

Remifentanil discontinuation is associated with an increased risk of ICU-acquired infection, an observation that reiterates previous reports on the negative effects of opioid withdrawal on the immune system.

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Sedation practice in the intensive care unit: a UK national survey

Henrik Reschreiter, Matt Maiden, Atul Kapila Critical Care 2008, 12:R152 (1 December 2008)

Abstract | Full text | PDF | PubMed

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