Table 3 |
|||||
|
Comparison of outcome between daily interruption of sedation and sedation algorithm |
|||||
|
Daily interruption of sedation n = 36 |
Sedation algorithm n = 38 |
P value |
|||
|
Median |
95% CI |
Median |
95% CI |
||
|
|
|||||
|
Total duration of mechanical ventilation, days |
6.7 |
4.1, 10.4 |
3.9 |
2.9, 4.9 |
0.0003 |
|
Intensive care unit length of stay, days |
15 |
9.1, 21.2 |
8 |
6.5, 8.7 |
< 0.0001 |
|
Hospital length of stay, days |
23 |
14.8, 28.7 |
12 |
11.3, 16.0 |
0.01 |
|
|
|||||
|
Median |
IQR |
Median |
IQR |
||
|
|
|||||
|
28-day ventilator-free survival |
16.1 |
0.00, 21.77 |
23.1 |
19.16, 25.06 |
0.004 |
|
Midazolam equivalents, mg/kg-day |
0.2 |
0.01, 1.48 |
0.4 |
0.01, 1.32 |
0.70 |
|
Fentanyl equivalents, μg/kg-day |
0.5 |
0.09, 2.43 |
1.2 |
0.12, 2.44 |
0.36 |
|
Propofol, μg/kg-day |
0 |
0.0, 5817.0 |
0 |
0.0, 6589.0 |
0.39 |
|
|
|||||
|
CI, confidence interval; IQR, interquartile range. |
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|
de Wit et al. Critical Care 2008 12:R70 doi:10.1186/cc6908 |
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