Critical Care | Volume 12 Issue 4

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	Volume 12 Issue 4
	Comment
	Commentary A call to arms to reduce premature deaths by using inexpensive resuscitation care Sam A Warren, Graham Nichol Critical Care 2008, 12:173 (19 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Opioid-induced constipation in intensive care patients: relief in sight? Daniel Chappell, Markus Rehm, Peter Conzen Critical Care 2008, 12:161 (1 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Normal adrenocortical function on initial testing in the intensive care unit: not a long-term warranty Pierre-Edouard Bollaert Critical Care 2008, 12:163 (2 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Breathing easier – good news from air medicine Thomas Judge Critical Care 2008, 12:164 (10 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids for community-acquired pneumonia: time to act! Djillali Annane, G Umberto Meduri Critical Care 2008, 12:166 (14 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Pandemic influenza: are we prepared to face our obligations? Boris P Ehrenstein Critical Care 2008, 12:165 (15 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary How to prevent leaky vessels during reperfusion? Just keep that glycocalyx sealant in place! Jurgen WGE VanTeeffelen Critical Care 2008, 12:167 (15 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary High mobility group box-1 protein – one step closer to the clinic? Tom Mollnes Critical Care 2008, 12:168 (17 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury Sean M Bagshaw, Patrick D Brophy, Dinna Cruz, Claudio Ronco Critical Care 2008, 12:169 (24 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Nebulised heparin: a new approach to the treatment of acute lung injury? Peter M Suter Critical Care 2008, 12:170 (25 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis therapy: what's the best for the mitochondria? Florian Wagner, Peter Radermacher, Michael Georgieff, Enrico Calzia Critical Care 2008, 12:171 (6 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Recently published papers: Renal replacement therapy: which route and how much? Intracerebral haematomas: does the size matter? beta blockers and steroids: will we ever know? Vlad Kushakovsky, Richard Venn Critical Care 2008, 12:172 (14 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Understanding cardiac output Jean-Louis Vincent Critical Care 2008, 12:174 (22 August 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Bench-to-bedside review: Latest results in hemorrhagic shock Martin K Angele, Christian P Schneider, Irshad H Chaudry Critical Care 2008, 12:218 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentation Nicholas Stollenwerk, Richart W Harper, Christian E Sandrock Critical Care 2008, 12:219 (17 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Avoiding pitfalls in critical care meta-analysis – funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy Michael C Reade, Anthony Delaney, Michael J Bailey, Derek C Angus Critical Care 2008, 12:220 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Liberation from mechanical ventilation Mohamad F El-Khatib, Pierre Bou-Khalil Critical Care 2008, 12:221 (6 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Metabolism and nutrition Michaël P Casaer, Dieter Mesotten, Miet RC Schetz Critical Care 2008, 12:222 (19 August 2008) Abstract \| Full text \| PDF \| PubMed
	Report
	Journal club critique Black Hawk Down: The evolution of resuscitation strategies in massive traumatic hemorrhage Deepika Mohan, Eric B Milbrandt, Louis H Alarcon Critical Care 2008, 12:305 (23 July 2008) Full text \| PDF \| PubMed
	Book report Infectious diseases in the paediatric intensive care unit Walter Zingg, Stephan Harbarth Critical Care 2008, 12:306 (25 July 2008) Abstract \| Full text \| PDF
	Research
	Research Procalcitonin in liver transplantation: are high levels due to donors or recipients? Daniel Eyraud, Saïd Ben Ayed, Marie Tanguy, Corinne Vézinet, Jean Siksik, Maguy Bernard, Sylvia Fratéa, Marie Movschin, Jean-Christophe Vaillant, Pierre Coriat, Laurent Hannoun Critical Care 2008, 12:R85 (4 July 2008) Abstract \| Full text \| PDF \| PubMed
	Research Danaparoid sodium attenuates the increase in inflammatory cytokines and preserves organ function in endotoxemic rats Toshiaki Iba, Taku Miyasho Critical Care 2008, 12:R86 (6 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest Joost J Jimmink, Jan M Binnekade, Frederique Paulus, Elisebeth MH Mathus-Vliegen, Marcus J Schultz, Margreeth B Vroom Critical Care 2008, 12:R87 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Normal cooling practices and the time taken to reach therapeutic hypothermia after out-of-hospital cardiac arrest are not affected by body composition.
	Research Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration Tomas Regueira, Bertram Bänziger, Siamak Djafarzadeh, Sebastian Brandt, Jose Gorrasi, Jukka Takala, Philipp M Lepper, Stephan M Jakob Critical Care 2008, 12:R88 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Improvement in liver mitochondrial respiration, implicated in the development of sepsis-induced organ failure, was linked to the effect of norepinephrine on liver cells in pigs with experimental sepsis.
	Research Risks associated with magnetic resonance imaging and cervical collar in comatose, blunt trauma patients with negative comprehensive cervical spine computed tomography and no apparent spinal deficit C Michael Dunham, Brian P Brocker, B David Collier, David J Gemmel Critical Care 2008, 12:R89 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Gastrointestinal Failure score in critically ill patients: a prospective observational study Annika Reintam, Pille Parm, Reet Kitus, Joel Starkopf, Hartmut Kern Critical Care 2008, 12:R90 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A scoring system combining food intolerance and intra-abdominal hypertension for assessment of gastrointestinal function has a high predictive value for intensive care unit mortality, shows a prospective study in 264 patients.
	Research Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome Bernard Lambermont, Alexandre Ghuysen, Nathalie Janssen, Philippe Morimont, Gary Hartstein, Paul Gerard, Vincent D'Orio Critical Care 2008, 12:R91 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Health care costs, long-term survival, and quality of life following intensive care unit admission after cardiac arrest Jürgen Graf, Cecile Mühlhoff, Gordon S Doig, Sebastian Reinartz, Kirsten Bode, Robert Dujardin, Karl-Christian Koch, Elke Roeb, Uwe Janssens Critical Care 2008, 12:R92 (18 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Circuit life span in critically ill children on continuous renal replacement treatment: a prospective observational evaluation study Jimena del Castillo, Jesús López-Herce, Elena Cidoncha, Javier Urbano, Santiago Mencía, Maria J Santiago, Jose M Bellón Critical Care 2008, 12:R93 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays Alexander Lukasz, Julian Hellpap, Rüdiger Horn, Jan T Kielstein, Sascha David, Hermann Haller, Philipp Kümpers Critical Care 2008, 12:R94 (29 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Reliability of diagnostic coding in intensive care patients Benoît Misset, Didier Nakache, Aurélien Vesin, Mickael Darmon, Maïté Garrouste-Orgeas, Bruno Mourvillier, Christophe Adrie, Sébastian Pease, Marie-Aliette de Beauregard, Dany Goldgran-Toledano, Elisabeth Métais, Jean-François Timsit, The Outcomerea Database Investigators Critical Care 2008, 12:R95 (29 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study Michael Haase, Rinaldo Bellomo, David Story, Piers Davenport, Anja Haase-Fielitz Critical Care 2008, 12:R96 (1 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research Prevalence of sleep disturbances and long-term reduced health-related quality of life after critical care: a prospective multicenter cohort study Lotti Orwelius, Anders Nordlund, Peter Nordlund, Ulla Edéll-Gustafsson, Folke Sjöberg Critical Care 2008, 12:R97 (1 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury Regula Meier, Markus Béchir, Silke Ludwig, Jutta Sommerfeld, Marius Keel, Peter Steiger, Reto Stocker, John F Stover Critical Care 2008, 12:R98 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Combined milrinone and enteral metoprolol therapy in patients with septic myocardial depression Christian A Schmittinger, Martin W Dünser, Maria Haller, Hanno Ulmer, Günter Luckner, Christian Torgersen, Stefan Jochberger, Walter R Hasibeder Critical Care 2008, 12:R99 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release Mian Zhou, Asha Jacob, Natalie Ho, Michael Miksa, Rongqian Wu, Subir R Maitra, Ping Wang Critical Care 2008, 12:R100 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients Mette M Berger, Ludivine Soguel, Alan Shenkin, Jean-Pierre Revelly, Christophe Pinget, Malcolm Baines, René L Chioléro Critical Care 2008, 12:R101 (7 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats Yung-Yang Liu, Cheng-Hung Lee, Rejmon Dedaj, Hang Zhao, Hicham Mrabat, Aviva Sheidlin, Olga Syrkina, Pei-Ming Huang, Hari G Garg, Charles A Hales, Deborah A Quinn Critical Care 2008, 12:R102 (8 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary Hyaluronan has been identified as an important modulator in many physiological processes, and the high molecular weight form has been shown to inhibit sepsis-induced lung injury in an animal model.
	Research Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment Li-Fu Li, Shuen-Kuei Liao, Chung-Chi Huang, Ming-Jui Hung, Deborah A Quinn Critical Care 2008, 12:R103 (9 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep Kristine Waerhaug, Vladimir N Kuklin, Mikhail Y Kirov, Mikhail A Sovershaev, Bodil Langbakk, Ole C Ingebretsen, Kirsti Ytrehus, Lars J Bjertnaes Critical Care 2008, 12:R104 (15 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital David Bruce, Tim JC Nokes Critical Care 2008, 12:R105 (15 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Time course of plasma gelsolin concentrations during severe sepsis in critically ill surgical patients HaiHong Wang, BaoLi Cheng, QiXing Chen, ShuiJing Wu, Chen Lv, GuoHao Xie, Yue Jin, XiangMing Fang Critical Care 2008, 12:R106 (17 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Patients with severe sepsis have lower plasma gelsolin levels than non-septic critically ill patients, and the correlation of recovered levels with clinical improvement suggests a potential role for plasma gelsolin as a marker for severe sepsis.
	Research Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro Natalie M Otto, Ralf Schindler, Andreas Lun, Olaf Boenisch, Ulrich Frei, Michael Oppert Critical Care 2008, 12:R107 (18 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator-induced lung injury Je Kim, Min Suk, Dae Yoon, Hye Kim, Ki Jung, Eun Kang, Sung Lee, Sang Lee, In Suh, Chol Shin, Jae Shim, Kwang In, Se Yoo, Kyung Kang Critical Care 2008, 12:R108 (22 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prognostic value of brain natriuretic peptide in acute pulmonary embolism Guillaume Coutance, Olivier Le Page, Ted Lo, Martial Hamon Critical Care 2008, 12:R109 (22 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications José Lopes, Paulo Fernandes, Sofia Jorge, Sara Gonçalves, António Alvarez, Zélia Costa e Silva, Carlos França, Mateus Prata Critical Care 2008, 12:R110 (28 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Tirofiban preserves platelet loss during continuous renal replacement therapy in a randomised prospective open-blinded pilot study Andreas Link, Matthias Girndt, Simina Selejan, Ranja Rbah, Michael Böhm Critical Care 2008, 12:R111 (29 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial Jon Pérez-Bárcena, Juan A Llompart-Pou, Javier Homar, Josep M Abadal, Joan M Raurich, Guillem Frontera, Marta Brell, Javier Ibáñez, Jordi Ibáñez Critical Care 2008, 12:R112 (29 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Applying logic to pulmonary artery catheter use Horst E Kunig, Michael R Pinsky, Lothar Engelmann Critical Care 2008, 12:421 (7 July 2008) Abstract \| Full text \| PDF \| PubMed
	Letter The complications of percutaneous endoscopic gastrostomy Julien Bordes, Emmanuel Hornez, Nadia Kenane, Christophe Carrere, Yves Asencio, Philippe Goutorbe Critical Care 2008, 12:422 (23 July 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Acute kidney injury: time to shift from creatinine to the estimated glomerular filtration rate? Giuseppe Lippi, Gian Cesare Guidi Critical Care 2008, 12:423 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Is "safe effective glucose control" effective and safe? Marcus J Schultz, Greet Berghe Critical Care 2008, 12:424 (6 August 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Role of the eosinophil count in discriminating the severity of community-acquired pneumonia in HIV-infected patients Rafel Perelló, Oscar Miró, Josep M Miró, Asunción Moreno Critical Care 2008, 12:425 (13 August 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Unanswered questions from Corticus and pragmatic suggestions Wolfgang Bauer, Jonathan Ball, Mike Grounds Critical Care 2008, 12:426 (14 August 2008) Abstract \| Full text \| PDF \| PubMed

	Volume 12 Issue 4
	Comment
	Commentary A call to arms to reduce premature deaths by using inexpensive resuscitation care Sam A Warren, Graham Nichol Critical Care 2008, 12:173 (19 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Opioid-induced constipation in intensive care patients: relief in sight? Daniel Chappell, Markus Rehm, Peter Conzen Critical Care 2008, 12:161 (1 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Normal adrenocortical function on initial testing in the intensive care unit: not a long-term warranty Pierre-Edouard Bollaert Critical Care 2008, 12:163 (2 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Breathing easier – good news from air medicine Thomas Judge Critical Care 2008, 12:164 (10 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids for community-acquired pneumonia: time to act! Djillali Annane, G Umberto Meduri Critical Care 2008, 12:166 (14 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Pandemic influenza: are we prepared to face our obligations? Boris P Ehrenstein Critical Care 2008, 12:165 (15 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary How to prevent leaky vessels during reperfusion? Just keep that glycocalyx sealant in place! Jurgen WGE VanTeeffelen Critical Care 2008, 12:167 (15 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary High mobility group box-1 protein – one step closer to the clinic? Tom Mollnes Critical Care 2008, 12:168 (17 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury Sean M Bagshaw, Patrick D Brophy, Dinna Cruz, Claudio Ronco Critical Care 2008, 12:169 (24 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Nebulised heparin: a new approach to the treatment of acute lung injury? Peter M Suter Critical Care 2008, 12:170 (25 July 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis therapy: what's the best for the mitochondria? Florian Wagner, Peter Radermacher, Michael Georgieff, Enrico Calzia Critical Care 2008, 12:171 (6 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Recently published papers: Renal replacement therapy: which route and how much? Intracerebral haematomas: does the size matter? beta blockers and steroids: will we ever know? Vlad Kushakovsky, Richard Venn Critical Care 2008, 12:172 (14 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Understanding cardiac output Jean-Louis Vincent Critical Care 2008, 12:174 (22 August 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Bench-to-bedside review: Latest results in hemorrhagic shock Martin K Angele, Christian P Schneider, Irshad H Chaudry Critical Care 2008, 12:218 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentation Nicholas Stollenwerk, Richart W Harper, Christian E Sandrock Critical Care 2008, 12:219 (17 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Avoiding pitfalls in critical care meta-analysis – funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy Michael C Reade, Anthony Delaney, Michael J Bailey, Derek C Angus Critical Care 2008, 12:220 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Liberation from mechanical ventilation Mohamad F El-Khatib, Pierre Bou-Khalil Critical Care 2008, 12:221 (6 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Metabolism and nutrition Michaël P Casaer, Dieter Mesotten, Miet RC Schetz Critical Care 2008, 12:222 (19 August 2008) Abstract \| Full text \| PDF \| PubMed
	Report
	Journal club critique Black Hawk Down: The evolution of resuscitation strategies in massive traumatic hemorrhage Deepika Mohan, Eric B Milbrandt, Louis H Alarcon Critical Care 2008, 12:305 (23 July 2008) Full text \| PDF \| PubMed
	Book report Infectious diseases in the paediatric intensive care unit Walter Zingg, Stephan Harbarth Critical Care 2008, 12:306 (25 July 2008) Abstract \| Full text \| PDF
	Research
	Research Procalcitonin in liver transplantation: are high levels due to donors or recipients? Daniel Eyraud, Saïd Ben Ayed, Marie Tanguy, Corinne Vézinet, Jean Siksik, Maguy Bernard, Sylvia Fratéa, Marie Movschin, Jean-Christophe Vaillant, Pierre Coriat, Laurent Hannoun Critical Care 2008, 12:R85 (4 July 2008) Abstract \| Full text \| PDF \| PubMed
	Research Danaparoid sodium attenuates the increase in inflammatory cytokines and preserves organ function in endotoxemic rats Toshiaki Iba, Taku Miyasho Critical Care 2008, 12:R86 (6 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest Joost J Jimmink, Jan M Binnekade, Frederique Paulus, Elisebeth MH Mathus-Vliegen, Marcus J Schultz, Margreeth B Vroom Critical Care 2008, 12:R87 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Normal cooling practices and the time taken to reach therapeutic hypothermia after out-of-hospital cardiac arrest are not affected by body composition.
	Research Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration Tomas Regueira, Bertram Bänziger, Siamak Djafarzadeh, Sebastian Brandt, Jose Gorrasi, Jukka Takala, Philipp M Lepper, Stephan M Jakob Critical Care 2008, 12:R88 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Improvement in liver mitochondrial respiration, implicated in the development of sepsis-induced organ failure, was linked to the effect of norepinephrine on liver cells in pigs with experimental sepsis.
	Research Risks associated with magnetic resonance imaging and cervical collar in comatose, blunt trauma patients with negative comprehensive cervical spine computed tomography and no apparent spinal deficit C Michael Dunham, Brian P Brocker, B David Collier, David J Gemmel Critical Care 2008, 12:R89 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Gastrointestinal Failure score in critically ill patients: a prospective observational study Annika Reintam, Pille Parm, Reet Kitus, Joel Starkopf, Hartmut Kern Critical Care 2008, 12:R90 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A scoring system combining food intolerance and intra-abdominal hypertension for assessment of gastrointestinal function has a high predictive value for intensive care unit mortality, shows a prospective study in 264 patients.
	Research Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome Bernard Lambermont, Alexandre Ghuysen, Nathalie Janssen, Philippe Morimont, Gary Hartstein, Paul Gerard, Vincent D'Orio Critical Care 2008, 12:R91 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Health care costs, long-term survival, and quality of life following intensive care unit admission after cardiac arrest Jürgen Graf, Cecile Mühlhoff, Gordon S Doig, Sebastian Reinartz, Kirsten Bode, Robert Dujardin, Karl-Christian Koch, Elke Roeb, Uwe Janssens Critical Care 2008, 12:R92 (18 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Circuit life span in critically ill children on continuous renal replacement treatment: a prospective observational evaluation study Jimena del Castillo, Jesús López-Herce, Elena Cidoncha, Javier Urbano, Santiago Mencía, Maria J Santiago, Jose M Bellón Critical Care 2008, 12:R93 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays Alexander Lukasz, Julian Hellpap, Rüdiger Horn, Jan T Kielstein, Sascha David, Hermann Haller, Philipp Kümpers Critical Care 2008, 12:R94 (29 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Reliability of diagnostic coding in intensive care patients Benoît Misset, Didier Nakache, Aurélien Vesin, Mickael Darmon, Maïté Garrouste-Orgeas, Bruno Mourvillier, Christophe Adrie, Sébastian Pease, Marie-Aliette de Beauregard, Dany Goldgran-Toledano, Elisabeth Métais, Jean-François Timsit, The Outcomerea Database Investigators Critical Care 2008, 12:R95 (29 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study Michael Haase, Rinaldo Bellomo, David Story, Piers Davenport, Anja Haase-Fielitz Critical Care 2008, 12:R96 (1 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research Prevalence of sleep disturbances and long-term reduced health-related quality of life after critical care: a prospective multicenter cohort study Lotti Orwelius, Anders Nordlund, Peter Nordlund, Ulla Edéll-Gustafsson, Folke Sjöberg Critical Care 2008, 12:R97 (1 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury Regula Meier, Markus Béchir, Silke Ludwig, Jutta Sommerfeld, Marius Keel, Peter Steiger, Reto Stocker, John F Stover Critical Care 2008, 12:R98 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Combined milrinone and enteral metoprolol therapy in patients with septic myocardial depression Christian A Schmittinger, Martin W Dünser, Maria Haller, Hanno Ulmer, Günter Luckner, Christian Torgersen, Stefan Jochberger, Walter R Hasibeder Critical Care 2008, 12:R99 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release Mian Zhou, Asha Jacob, Natalie Ho, Michael Miksa, Rongqian Wu, Subir R Maitra, Ping Wang Critical Care 2008, 12:R100 (4 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients Mette M Berger, Ludivine Soguel, Alan Shenkin, Jean-Pierre Revelly, Christophe Pinget, Malcolm Baines, René L Chioléro Critical Care 2008, 12:R101 (7 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats Yung-Yang Liu, Cheng-Hung Lee, Rejmon Dedaj, Hang Zhao, Hicham Mrabat, Aviva Sheidlin, Olga Syrkina, Pei-Ming Huang, Hari G Garg, Charles A Hales, Deborah A Quinn Critical Care 2008, 12:R102 (8 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary Hyaluronan has been identified as an important modulator in many physiological processes, and the high molecular weight form has been shown to inhibit sepsis-induced lung injury in an animal model.
	Research Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment Li-Fu Li, Shuen-Kuei Liao, Chung-Chi Huang, Ming-Jui Hung, Deborah A Quinn Critical Care 2008, 12:R103 (9 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep Kristine Waerhaug, Vladimir N Kuklin, Mikhail Y Kirov, Mikhail A Sovershaev, Bodil Langbakk, Ole C Ingebretsen, Kirsti Ytrehus, Lars J Bjertnaes Critical Care 2008, 12:R104 (15 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital David Bruce, Tim JC Nokes Critical Care 2008, 12:R105 (15 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Time course of plasma gelsolin concentrations during severe sepsis in critically ill surgical patients HaiHong Wang, BaoLi Cheng, QiXing Chen, ShuiJing Wu, Chen Lv, GuoHao Xie, Yue Jin, XiangMing Fang Critical Care 2008, 12:R106 (17 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Patients with severe sepsis have lower plasma gelsolin levels than non-septic critically ill patients, and the correlation of recovered levels with clinical improvement suggests a potential role for plasma gelsolin as a marker for severe sepsis.
	Research Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro Natalie M Otto, Ralf Schindler, Andreas Lun, Olaf Boenisch, Ulrich Frei, Michael Oppert Critical Care 2008, 12:R107 (18 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator-induced lung injury Je Kim, Min Suk, Dae Yoon, Hye Kim, Ki Jung, Eun Kang, Sung Lee, Sang Lee, In Suh, Chol Shin, Jae Shim, Kwang In, Se Yoo, Kyung Kang Critical Care 2008, 12:R108 (22 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prognostic value of brain natriuretic peptide in acute pulmonary embolism Guillaume Coutance, Olivier Le Page, Ted Lo, Martial Hamon Critical Care 2008, 12:R109 (22 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications José Lopes, Paulo Fernandes, Sofia Jorge, Sara Gonçalves, António Alvarez, Zélia Costa e Silva, Carlos França, Mateus Prata Critical Care 2008, 12:R110 (28 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Tirofiban preserves platelet loss during continuous renal replacement therapy in a randomised prospective open-blinded pilot study Andreas Link, Matthias Girndt, Simina Selejan, Ranja Rbah, Michael Böhm Critical Care 2008, 12:R111 (29 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial Jon Pérez-Bárcena, Juan A Llompart-Pou, Javier Homar, Josep M Abadal, Joan M Raurich, Guillem Frontera, Marta Brell, Javier Ibáñez, Jordi Ibáñez Critical Care 2008, 12:R112 (29 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Applying logic to pulmonary artery catheter use Horst E Kunig, Michael R Pinsky, Lothar Engelmann Critical Care 2008, 12:421 (7 July 2008) Abstract \| Full text \| PDF \| PubMed
	Letter The complications of percutaneous endoscopic gastrostomy Julien Bordes, Emmanuel Hornez, Nadia Kenane, Christophe Carrere, Yves Asencio, Philippe Goutorbe Critical Care 2008, 12:422 (23 July 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Acute kidney injury: time to shift from creatinine to the estimated glomerular filtration rate? Giuseppe Lippi, Gian Cesare Guidi Critical Care 2008, 12:423 (25 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Is "safe effective glucose control" effective and safe? Marcus J Schultz, Greet Berghe Critical Care 2008, 12:424 (6 August 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Role of the eosinophil count in discriminating the severity of community-acquired pneumonia in HIV-infected patients Rafel Perelló, Oscar Miró, Josep M Miró, Asunción Moreno Critical Care 2008, 12:425 (13 August 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Unanswered questions from Corticus and pragmatic suggestions Wolfgang Bauer, Jonathan Ball, Mike Grounds Critical Care 2008, 12:426 (14 August 2008) Abstract \| Full text \| PDF \| PubMed

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