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Is "safe effective glucose control" effective and safe?

Marcus J Schultz1,2* and Greet V Berghe3

Author Affiliations

1 Department of Intensive Care, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands

2 Laboratory of Experimental Intensive Care and Anesthesiology (L·E·I·C·A), Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands

3 Department of Intensive Care, Catholic University Leuven, Leuven, Belgium

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Critical Care 2008, 12:424 doi:10.1186/cc6960

Published: 6 August 2008

First paragraph (this article has no abstract)

Since tight glucose control (TGC) inevitably comes with a risk of hypoglycemia, Krinsley and Preiser [1] suggest the use of a stepwise approach to glucose control, which they call "safe, effective glucose control" (SEGC), and that targets an intermediate blood glucose level (BGL). SEGC is intended to decrease the rate of hyperglycemia while reducing the adverse effects of severe hypoglycemia.