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Is "safe effective glucose control" effective and safe?

Marcus J Schultz1,2 email and Greet Van den Berghe3 email

1Department of Intensive Care, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands

2Laboratory of Experimental Intensive Care and Anesthesiology (L·E·I·C·A), Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands

3Department of Intensive Care, Catholic University Leuven, Leuven, Belgium

author email corresponding author email

Critical Care 2008, 12:424doi:10.1186/cc6960

Published: 6 August 2008


See related commentary by Krinsley and Preiser, http://ccforum.com/content/12/3/149

First paragraph (this article has no abstract)

Since tight glucose control (TGC) inevitably comes with a risk of hypoglycemia, Krinsley and Preiser [1] suggest the use of a stepwise approach to glucose control, which they call "safe, effective glucose control" (SEGC), and that targets an intermediate blood glucose level (BGL). SEGC is intended to decrease the rate of hyperglycemia while reducing the adverse effects of severe hypoglycemia.


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