Critical Care

official impact factor 4.60

Highly Access Letter

Unanswered questions from Corticus and pragmatic suggestions

Wolfgang Bauer, Jonathan Ball* and Mike Grounds

Author Affiliations

General Intensive Care Unit, St George's Hospital, London, SW17 0QT, UK

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Critical Care 2008, 12:426 doi:10.1186/cc6967

Published: 14 August 2008

First paragraph (this article has no abstract)

Professor Vincent, in an eloquent commentary in Critical Care, calls for a further trial into supraphysiological cortico-steroid therapy in vasopressor-resistant shock [1]. Together with editorials in several of the intensive care journals, he has pointed out many of the shortcomings in the Corticus trial [2]. We would like to add to this chorus by posing a further question to the authors and putting forward some suggestions. Regrettably, we are prohibited from addressing these directly due to the Letters policy of the journal in which the original paper was published.