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Unanswered questions from Corticus and pragmatic suggestions

Wolfgang Bauer, Jonathan Ball email and Mike Grounds

General Intensive Care Unit, St George's Hospital, London, SW17 0QT, UK

author email corresponding author email

Critical Care 2008, 12:426doi:10.1186/cc6967

Published: 14 August 2008


See related commentary by Vincent, http://ccforum.com/content/12/2/141

First paragraph (this article has no abstract)

Professor Vincent, in an eloquent commentary in Critical Care, calls for a further trial into supraphysiological cortico-steroid therapy in vasopressor-resistant shock [1]. Together with editorials in several of the intensive care journals, he has pointed out many of the shortcomings in the Corticus trial [2]. We would like to add to this chorus by posing a further question to the authors and putting forward some suggestions. Regrettably, we are prohibited from addressing these directly due to the Letters policy of the journal in which the original paper was published.


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