Table 4 |
||||||
|
Outcome variables with detail of cardiac and trauma patients |
||||||
| Variable |
All |
Cardiac surgery |
Trauma |
|||
|
|
||||||
| AOX |
Placebo |
AOX |
Placebo |
AOX |
Placebo |
|
| Number |
200 |
113 |
66 |
|||
| Number |
102 |
98 |
57 |
56 |
34 |
32 |
| Prior renal failure |
61 (30.5%) |
49 (43.4%)a |
10 (15.1%) |
|||
| 25 |
36 |
20 |
29 |
6 |
4 |
|
| Acute kidney injury |
66 (33%) |
50 (44.2%)a |
13 (19.7%) |
|||
| 29 (30%) |
36 (37%) |
21 (37%) |
29 (52%)b |
7 |
6 |
|
| ARF increase of 50 μmol/L |
32 (16%) |
29 (27.5%)a |
3 (15.2%) |
|||
| 15 (15%) |
17 (17% |
13 (23% |
16 (29%) |
2 |
1 |
|
| ARF increase of 90 μmol/L |
16 (8%) |
15 (13.3%)a |
1 (1.5%) |
|||
| 7 (7%) |
9 (9%) |
6 (11% |
9 (16%) |
1 |
0 |
|
| CVVH |
7 (3.5%) |
6 (5.3%) |
1 (1.5%) |
|||
| 6 |
1c,d |
5 |
1 |
1 |
0 |
|
| Persistent renal failure |
11 (5.5%) |
10 (8.8%) |
1 (1.5%) |
|||
| 4 (4%) |
7 (7%) |
3 (5%) |
7 (13%)e |
1 |
0 |
|
| Ventilator-free days |
26.3 ± 5.5 |
26.6 ± 5.3 |
25.2 ± 6.3 |
|||
| 26.1 ± 5.7 |
26.6 ± 5.2 |
25.9 ± 6.7 |
27.3 ± 3.3e |
25.5 ± 4.6 |
24.9 ± 7.7 |
|
| Infections (patients with) |
70 |
30 |
30 |
|||
| 36 |
34 |
14 |
16 |
17 |
13 |
|
| Infectious episodes |
91 |
39 |
39 |
|||
| 45 |
46 |
19 |
20 |
21 |
18 |
|
| Pneumonia episodes |
30 |
16 |
14 |
|||
| 14 |
16 |
7 |
9 |
7 |
7 |
|
| Length of stay, days |
||||||
| In the ICU |
5.6 ± 5.5 |
5.2 ± 5.1 |
6.3 ± 6.5 |
|||
| 5.8 ± 5.4 |
5.4 ± 5.7 |
5.8 ± 6.0 |
4.7 ± 4.0 |
5.8 ± 4.4 |
6.8 ± 8.3 |
|
| In intermediate care |
5.0 ± 5.5 |
3.6 ± 3.5 |
6.5 ± 7.2 |
|||
| 4.5 ± 4.9 |
5.5 ± 6.0 |
3.3 ± 4.2 |
3.4 ± 4.1 |
5.9 ± 7.1 |
7.1 ± 7.4 |
|
| In the hospital |
24 ± 20 |
19 ± 13 |
32 ± 22 |
|||
| 23 ± 20 |
26 ± 20 |
20 ± 14 |
19 ± 13 |
26 ± 19 |
39 ± 24f |
|
| Deaths |
||||||
| In the ICU |
14 (7%) |
11 (9.7%) |
2 (3%) |
|||
| 8 |
5 |
6 |
5 |
2 |
0g |
|
| In hospital |
23 (11.5%) |
12 (10.6%) |
8 (12.1%) |
|||
| 14 |
9 |
8 |
6 |
6 |
2g |
|
| At 3 months |
25 (12.5%) |
16 (14.2%) |
8 (12.1%) |
|||
| 14 |
11 |
8 |
8 |
6 |
2g |
|
|
|
||||||
|
Data are presented as number (percentage) and mean ± standard deviation. aP < 0.001. bP = 0.109. cP = 0.05. dSee comment in Results section. eP = 0.17. fP = 0.016. gP = 0.16. Superscript a refers to comparison between diagnostic categories. Superscripts b, c, e, f, and g refer to comparison between antioxidant (AOX) and placebo groups. ARF, acute renal failure; CVVH, continuous veno-venous hemofiltration; ICU, intensive care unit. |
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|
Berger et al. Critical Care 2008 12:R101 doi:10.1186/cc6981 |
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