Table 2

Physiologic conditions at the beginning and the end of ventilation

Nonventilated room air

6 ml/kg tidal volume room air

30 ml/kg tidal volume room air

PH

7.40 ± 0.05

7.35 ± 0.02

7.33 ± 0.06

Arterial oxygen pressure (mmHg)

98.7 ± 0.6

82.3 ± 7.5

86.1 ± 1.3

Arterial carbon dioxide pressure (mmHg)

40.2 ± 0.5

39.1 ± 1.1

35.3 ± 1.9

Mean arterial pressure (mmHg)

Start

86 ± 1.9

85.3 ± 3.0

84.6 ± 2.3

End

85 ± 0.8

81.3 ± 2.2

73.5 ± 7.1

Peak inspiratory pressure (mmHg)

Start

9.5 ± 1.5

23.6 ± 2.6

End

11.7 ± 1.8

27.9 ± 3.8

Arterial blood gases and mean arterial pressure of normal nonventilated mice and of mice ventilated at tidal volumes of 6 ml/kg or 30 ml/kg for 5 hours (n = 10 per group).

Li et al. Critical Care 2008 12:R103   doi:10.1186/cc6983