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Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital

David Bruce and Tim JC Nokes*

Critical Care 2008, 12:R105 doi:10.1186/cc6987

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Which is the most effective strategy: early detection of coagulopathy with thromboelastometry or use of hemostatic factors or both?

Jean-Stephane David, Virginie Marchal, Albrice Levrat, Kenji Inaba Critical Care 2011, 15:433 (13 June 2011)

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Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity

Benny Sørensen, Donat R Spahn, Petra Innerhofer, Michael Spannagl, Rolf Rossaint Critical Care 2011, 15:201 (12 January 2011)

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Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate

Herbert Schöchl, Ulrike Nienaber, Georg Hofer, Wolfgang Voelckel, Csilla Jambor, Gisela Scharbert, Sibylle Kozek-Langenecker, Cristina Solomon Critical Care 2010, 14:R55 (7 April 2010)

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Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding

Kerstin S Schick, Jan M Fertmann, Karl-Walter Jauch, Johannes N Hoffmann Critical Care 2009, 13:R191 (30 November 2009)

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