|
Admission and outcome parameters of study patients |
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| Admission parameters |
IAH |
FI |
|||||
| Total |
Absent |
Present |
P |
Absent |
Present |
P |
|
|
|
|||||||
| Number of patients (%) |
264 ± 100.0 |
192 ± 72.3 |
72 ± 27.3 |
110 ± 41.7 |
154 ± 58.3 |
||
| Male sex (n [%]) |
166 ± 62.9 |
117 ± 60.9 |
49 ± 68.1 |
0.178 |
60 ± 54.5 |
106 ± 68.8 |
0.013 |
| Age (years) |
53.8 ± 20.0 |
52.3 ± 21.0 |
57.8 ± 16.8 |
0.047 |
48.6 ± 21.0 |
57.5 ± 18.5 |
<0.001 |
| Diabetes (n [%]) |
35 ± 13.3 |
26 ± 13.5 |
9 ± 12.5 |
0.502 |
11 ± 10.0 |
24 ± 15.6 |
0.128 |
| Readmission (n [%]) |
8 ± 3.0 |
6 ± 3.1 |
2 ± 2.8 |
0.622 |
2 ± 1.8 |
6 ± 3.9 |
0.287 |
| Sedation (n [%]) |
243 ± 92.0 |
174 ± 90.6 |
69 ± 95.8 |
0.125 |
98 ± 89.1 |
145 ± 94.2 |
0.103 |
| Vasoactive/inotrope (n [%]) |
200 ± 75.8 |
136 ± 70.8 |
64 ± 88.9 |
0.001 |
67 ± 60.9 |
133 ± 86.4 |
<0.001 |
| Surgical profile (n [%]) |
175 ± 66.3 |
122 ± 63.5 |
53 ± 73.7 |
0.080 |
67 ± 60.9 |
108 ± 70.1 |
0.077 |
| Laparatomy (n [%]) |
60 ± 23.3 |
21 ± 15.6 |
31 ± 43.7 |
<0.001 |
9 ± 8.4 |
51 ± 34.0 |
<0.001 |
| Enteral feeding (n [%]) |
49 ± 18.6 |
42 ± 21.9 |
7 ± 9.7 |
0.015 |
25 ± 22.7 |
24 ± 15.6 |
0.095 |
| APACHE II score (points) |
14.2 ± 7.7 |
13.5 ± 7.6 |
16.0 ± 7.7 |
0.016 |
11.8 ± 7.3 |
15.8 ± 7.6 |
<0.001 |
| BMI (kg/m2) |
27.6 ± 13.1 |
25.4 ± 4.6 |
33.1 ± 22.2 |
<0.001 |
25.8 ± 5.6 |
28.9 ± 16.4 |
0.080 |
| SOFA score (points) |
7.0 ± 4.2 |
6.3 ± 4.2 |
8.9 ± 3.6 |
<0.001 |
5.3 ± 4.2 |
8.2 ± 3.8 |
<0.001 |
| Fluid gain in first 24 hours (l) |
2.4 ± 3.6 |
2.0 ± 2.4 |
3.6 ± 5.5 |
0.001 |
1.7 ± 2.4 |
2.9 ± 4.2 |
0.007 |
| MAP (mmHg) |
81.5 ± 15.9 |
82.1 ± 16.4 |
80.5 ± 15.0 |
0.512 |
82.1 ± 15.8 |
81.3 ± 16.1 |
0.758 |
| IAP (mmHg) |
8.5 ± 4.7 |
6.5 ± 3.8 |
12.1 ± 4.0 |
<0.001 |
6.3 ± 4.0 |
9.5 ± 4.6 |
<0.001 |
| CVP (mmHg) |
11.6 ± 5.7 |
10.3 ± 4.9 |
14.3 ± 6.3 |
<0.001 |
10.4 ± 5.1 |
12.2 ± 5.9 |
0.031 |
| PIP (cmH2O) |
23.9 ± 6.2 |
22.6 ± 6.0 |
27.2 ± 5.2 |
<0.001 |
22.5 ± 6.5 |
24.8 ± 5.7 |
0.006 |
| PEEP (cmH2O) |
9.2 ± 4.2 |
8.5 ± 4.1 |
11.2 ± 3.7 |
<0.001 |
7.8 ± 4.1 |
10.2 ± 3.9 |
<0.001 |
| Lactate (mmol/l) |
4.6 ± 5.4 |
4.4 ± 4.6 |
4.9 ± 6.9 |
0.519 |
4.4 ± 4.9 |
4.7 ± 5.7 |
0.741 |
| FI (n [%]) |
124 ± 47.0 |
69 ± 35.9 |
55 ± 76.4 |
<0.001 |
- |
- |
|
| IAH (n [%]) |
42 ± 15.9 |
- |
- |
3 ± 2.7 |
39 ± 25.3 |
<0.001 |
|
| Gastrointestinal failure (FI+IAH; n [%]) |
36 ± 13.6 |
- |
36 ± 50.0 |
- |
36 ± 23.4 |
||
| Outcome parameters |
|||||||
| MV (days) |
7.4 ± 11.9 |
4.3 ± 6.1 |
15.5 ± 18.0 |
<0.001 |
3.6 ± 5.9 |
10.0 ± 14.1 |
<0.001 |
| ICU (days) |
8.8 ± 12.8 |
5.6 ± 7.3 |
17.5 ± 19.0 |
<0.001 |
4.8 ± 6.9 |
11.7 ± 15.1 |
<0.001 |
| ICU mortality (n [%]) |
39 ± 14.8 |
21 ± 10.9 |
18 ± 25.0 |
0.005 |
7 ± 6.4 |
32 ± 20.8 |
0.001 |
| 28-day mortality (n [%]) |
54 ± 20.5% |
36 ± 18.8% |
18 ± 25.0% |
0.171 |
13 ± 11.8% |
41 ± 26.6% |
<0.001 |
| 90-day mortality (n [%]) |
75 ± 28.4% |
48 ± 25.0% |
27 ± 37.5% |
0.033 |
17 ± 15.5% |
58 ± 37.7% |
0.002 |
|
The values are presented as mean ± standard deviation. APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; CVP, central venous pressure; FI, food intolerance; IAH, intra-abdominal hypertension; IAP, intra-abdominal pressure; ICU, intensive care unit; MAP, mean arterial pressure; MV, mechanical ventilation; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure; SOFA, Sequential Organ Failure Assessment. | |||||||
Reintam et al. Critical Care 2008 12:R90 doi:10.1186/cc6958 |
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