Table 2

Factors associated with the circuit life span


Circuit life span, hours
P value



Mean
Standard deviation


Age



     <12 months
29.1
32.8
0.33
     >12 months
33.3
35.5

Weight



     <10 kg
28.8
31.9
0.24
     >10 kg
34.3
37.0

Period of time



     1996–2001
27.0
25.0
0.43
     2002–2006
32.8
37.4

Pump type



     PRISMA
31.8
36.1
0.98
     BSM32
29.0
27.1

Catheter size



     Two 4 French catheters
12.5
8.6

     Double-lumen 5 French Double-lumen 6.5 French
25.7 34.2
25.4 37.8
0.07
     Double-lumen 8–9 French
22.8
20.8

     Double-lumen 10–11 French
36.1
38.6

     4–5 French
25.0
25.0
0.04
     6.5–11 French
33.0
36.3

Venous access



     Subclavian
34.2
27.6

     Femoral
30.5
34.4

     Jugular
21.2
21.9
0.12
     Other
38.2
40.5

Blood flow rate



     <50 mL per hour
29.9
34.5
0.33
     >50 mL per hour
32.8
33.2

Filter surface area



     0.04 m2
27.7
31.2

     0.15 m2
20.6
14.5
0.18
     0.4 m2
43.6
51

     0.6 m2
37.7
36.8

     0.9 m2
38.2
53.5

     0.04–0.15 m2
26.1
28.7
0.01
     0.4–0.6–0.9 m2
38.2
40.3

Filter membrane



     Polysulphone
28.5
28.5
0.18
     Acrylonitrile
32.0
35.3

Anticoagulation



     No heparine
31
16.6
0.15
     Heparine
31
34.6

Heparine dose



     <10 U/kg per hour
28.4
28.4
0.08
     >10 U/kg per hour
34.5
34.4

     <15 U/kg per hour
28.9
31.5
0.02
     >15 U/kg per hour
35.5
38.9

     <20 U/kg per hour
29.1
31.5
0.008
     >20 U/kg per hour
39.0
42.7

Hemodiafiltration



     Yes
34.0
36.6
0.001
     No
22.7
24.0

Ultrafiltration rates



     <25 mL/kg per hour
32.2
35.4
0.10
     >25 mL/kg per hour
21.0
17.2

Filtration fraction



     <10%
31.5
34.6
0.12
     >10%
18.3
13.3

Total effluent flow rate



     >35 mL/kg per hour
34.6
39.6
0.06
     <35 mL/kg per hour
25.8
22.9

Initial creatinine



     <2 mg/dL
32.4 26.5
36.0 22.3
0.39
     >2 mg/dL



Initial urea



     <60 mg/dL
30.9
34.1
0.99
     >60 mg/dL
30.4
32.0

Mortality



     Yes
32.6
36.8
0.94
     No
30.2
32.6

PRISM score



     <15
29.0
29.5
0.95
     >14
36.1
41.7

Lactic acid



     <4 mmol/L
28.7
29.9
0.91
     >4 mmol/L
34.7
39


PRISM, pediatric risk of mortality.

del Castillo et al. Critical Care 2008 12:R93   doi:10.1186/cc6965