Circuit lifespan during continuous renal replacement therapy: children and adults are not equal

doi:10.1186/cc7000

Critical Care
Volume 12
Issue 5

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Commentary

Circuit lifespan during continuous renal replacement therapy: children and adults are not equal

Zaccaria Ricci¹ , Isabella Guzzo² , Stefano Picca² and Sergio Picardo¹

¹Department of Pediatric Cardiology, Bambino Gesù Hospital, Piazza S. Onofrio 4 00100, Rome, Italy

²Department of Nephrology and Urology, Dialysis Unit, Bambino Gesù Hospital, Piazza S. Onofrio 4 00100, Rome, Italy

author email corresponding author email

Critical Care 2008, 12:178doi:10.1186/cc7000


Published:	16 September 2008

See related research by Castillo et al., http://ccforum.com/content/12/4/R93

Abstract

In the field of continuous renal replacement therapy (CRRT), session length, downtime and dose require detailed research, which will provide information important in relation to prescription, anticoagulation and circuit material choice (membrane type and size, vascular access site and size). In particular, it appears that many of the data currently existing in the literature and accepted regarding CRRT prescription and delivery in critically ill adult patients are not strictly applicable to the paediatric setting. Furthermore, many of the available paediatric studies are small, retrospective or underpowered. In paediatric CRRT, epidemiological investigations and prospective trials to investigate practical aspects of extracorporeal therapies are welcome and urgently needed.