Table 1

Characteristics of an optimal descriptor of organ dysfunction

Specific for the function of the organ system of interest
Comprehensive measure of function in that system
Sensitive to clinically important change in function
Recognizable to clinician
Increasing abnormality associated with increasing risk of adverse outcome
Not readily reversed by resuscitation
Objective
Measure of physiologic derangement, rather than treatment decision
Reliably, readily, and reproducibly measured
Inexpensive
Abnormal in one direction only
Single, continuous variable

Adapted from [4].

Khadaroo and Marshall Critical Care 2008 12:180   doi:10.1186/cc7001