Barbiturates for the treatment of intracranial hypertension after traumatic brain injury

doi:10.1186/cc7020

Critical Care
Volume 12
Issue 5

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Commentary

Barbiturates for the treatment of intracranial hypertension after traumatic brain injury

Sarice L Bassin and Thomas P Bleck

Department of Neurology, Northwestern University Feinberg School of Medicine, N Lake Shore Drive, Chicago, Illinois 60611, USA

author email corresponding author email

Critical Care 2008, 12:185doi:10.1186/cc7020


Published:	20 October 2008

See related research by Pérez-Barcena et al., http://ccforum.com/content/12/4/R112

Abstract

In their article on the use of barbiturates for the treatment of intracranial hypertension after traumatic brain injury, Perez-Barcena and colleagues conclude that thiopental was more effective than pentobarbital in decreasing intracranial pressure. Here we discuss the limitations of this study and review areas of controversy surrounding barbiturate use in neurocritical care.