Table 1

Characteristics of patients with AKI and ESRF

Factor
Advanced AKI without RRT (n = 935)
AKI on RRT (n = 1,847)
ESRF (n = 797)
P (AKI on RRT versus ESRF)

Male sex
67.2%
70.6%
59.6%
0.0002
Mean age ± SD (years)
60.1 ± 15.7
63.1 ± 15.4
55.3 ± 16.4
0.062
SOFA score on admission to ICU (median [range])
7 (0 to 17)
10 (1 to 22)
8 (1 to 8)
0.11
Organ failure on admission to ICUa (n; median [range])
1 (0 to 4)
2 (0 to 6)
0 (0 to 4)
<0.0001
Nonsurgical admission
65.2%
69%
54.8%
<0.0001
Emergency surgery
17.1%
13.2%
13.9%
0.64
Maximum organ failures in ICUa (n; median [range])
1 (0 to 6)
2 (0 to 6)
0 (0 to 5)
<0.0001
Mechanical ventilation
78%
91.3%
60.9%
<0.0001
Haemoglobin ≤ 9 g/dl on admission to ICU
20.6%
26.9%
42.7%
<0.0001
Cardiac surgery
10.2%
12.8%
11.4%
0.935
ICU mortality
40.6%
54.1%
20.8%
<0.0001
Hospital mortality
50.5%
61.6%
34.5%
<0.0001
Length of stay in ICU (days; median [range])
7 (1 to 270)
10 (1 to 219)
2 (1 to 64)
<0.0001

aExcluding renal failure. AKI, acute kidney injury; ESRF, end-stage renal failure; ICU, intensive care unit; OR = odds ratio; RRT, renal replacement therapy; SD, standard deviation; SOFA, Sequential Organ Failure Assessment.

Ostermann et al. Critical Care 2008 12:432   doi:10.1186/cc7085