Table 10 |
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|
Performance of various values of PetCO2 and duration of CPR for prediction of survival in patients with nonshockable initial rhythm in cardiac arrest |
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|
PetCO2 |
Cut-off (kPa [mmHg]) |
n |
Min-max (kPa [mmHg]) |
Mean ± SD (kPa [mmHg]) |
Sensitivity (%) |
Specificity (%) |
PPV (%) |
NPV (%) |
AUROC (95% CI) |
|
|
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|
initial |
≤1.3 (10) |
97 |
0.0–1.3 (0.0–10) |
0.66 ± 0.32 (5.1 ± 1.9) |
100 |
27 |
23 |
100 |
0.58 (0.52–0.63) |
|
>1.3 (10) |
336 |
1.4–8.4 (10.1–63.2) |
4.17 ± 2.12 (30.9 ± 15.8) |
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|
0–10 min |
≤1.7 (12.8) |
229 |
0.4–1.7 (3.5–12.8) |
0.99 ± 0.36 (7.1 ± 3.3) |
100 |
64 |
37 |
100 |
0.88 (0.84–0.91) |
|
>1.7 (12.8) |
204 |
1.8–5.6 (12.9–42.1) |
2.79 ± 0.86 (21.5 ± 6.2) |
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|
10 min |
≤1.6 (12.1) |
199 |
0.3–1.6 (2.2–12.1) |
1.03 ± 0.38 (7.6 ± 3.1) |
100 |
56 |
32 |
100 |
0.87 (0.83–0.91) |
|
>1.6 (12.1) |
234 |
1.7–7.2 (12.2–54.2) |
3.02 ± 1.08 (22.6 ± 6.5) |
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|
11–15 min |
≤1.7 (12.8) |
239 |
0.4–1.7 (3.4–12.8) |
0.99 ± 0.31 (7.3 ± 2.8) |
100 |
67 |
39 |
100 |
0.86 (0.83–0.90) |
|
>1.7 (12.8) |
194 |
1.4–5.1 (12.9–38.4) |
3.14 ± 0.81 (23.3 ± 6.7) |
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|
15 min |
≤1.9 (14.3) |
241 |
0.3–1.9 (2.4–14.3) |
1.12 ± 0.41 (7.9 ± 3.8) |
100 |
67 |
39 |
100 |
0.87 (0.84–0.91) |
|
>1.9 (14.3) |
192 |
2.1–6.1 (14.4–45.9) |
3.62 ± 0.94 (28.6 ± 7.5) |
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|
20 min |
≤2.1 (15.8) |
242 |
0.3–2.1 (2.3–15.8) |
0.91 ± 0.31 (7.2 ± 2.2) |
100 |
68 |
40 |
100 |
0.87 (0.84.0.91) |
|
>2.1 (15.8) |
190 |
2.3–7.8 (15.9–58.7) |
4.39–1.11 (33.1 ± 7.7) |
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|
max |
≤2.8 (21.1) |
231 |
0.8–2.8 (6.1–21.1) |
1.68 ± 0.44 (13.4 ± 3.5) |
100 |
65 |
38 |
100 |
0.89 (0.86–0.92) |
|
>2.8 (21.1) |
202 |
2.9–10.7 (21–80.5) |
5.26 ± 1.48 (39.1 ± 12.2) |
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|
Final |
≤1.6 (12.1) |
240 |
0.2–1.6 (1.9–12.1) |
0.97 ± 0.33 (6.9 ± 2.7) |
100 |
67 |
39 |
100 |
0.87 (0.84–0.91) |
|
>1.6 (12.1) |
193 |
1.9–6.6 (12.2–49.6) |
3.06 ± 0.97 (27.1 ± 7.2) |
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|
|
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|
'Nonshockable' was defined as asystole or pulseless electrical activity. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, restoration of spontaneous circulation; SD, standard deviation. |
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|
Kolar et al. Critical Care 2008 12:R115 doi:10.1186/cc7009 |
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