Table 3

Performance of various values of PetCO2 and duration of CPR for predicting ROSC in all patients with cardiac arrest

PetCO2

Cut-off (kPa [mmHg])

n

Min-max (kPa [mmHg])

Mean ± SD (kPa [mmHg])

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

AUROC (95% CI)


Initial

≤1.3 (≤10)

168

0.0–1.3 (0.0–10)

0.68 ± 0.34 (5.1 ± 2.5)

100

50

71

100

0.68 (0.63–0.72)

>1.3 (>10)

569

1.4–8.7 (10.1–65.4)

3.52 ± 1.93 (26.3 ± 14.5)

0 to 10 minutes

≤1.6 (≤12.1)

306

0.3–1.6 (2.3–12.1)

0.96 ± 0.34 (7.2 ± 2.6)

100

91

93

100

0.99 (0.99–1.00)

>1.6 (>12.1)

431

1.7–5.6 (12.2–42.1)

2.79 ± 0.82 (20.9 ± 0.8)

10 minutes

≤1.3 (≤9.8)

202

0.3–1.3 (2.3–9.8)

0.85 ± 0.31 (6.4 ± 2.1)

100

60

75

100

0.99 (0.98–0.99)

>1.3 (>9.8)

535

1.4–7.2 (9.9–54.2)

2.89 ± 1.09 (21.7 ± 8.2)

11–15 minutes

≤1.7 (≤12.8)

333

0.4–1.7 (3.1–12.8)

0.99 ± 0.30 (7.6 ± 2.2)

100

99

99

100

1.00 (0.99–1.00)

>1.7 (>12.8)

404

1.8–5.5 (12.8–41.4)

3.19 ± 0.77 (23.9 ± 4.8)

15 minutes

≤1.8 (≤13.6)

328

0.2–1.8 (1.5–13.5)

1.11 ± 0.39 (8.4 ± 2.8)

100

98

98

100

0.99 (0.99–1.00)

>1.8 (>13.6)

409

1.9–7.7 (13.6–57.9)

3.65 ± 0.98 (27.8 ± 7.4)

20 minutes

≤1.9 (≤14.3)

335

0.3–1.9 (2.3–14.3)

0.92 ± 0.29 (6.8 ± 2.1)

100

100

100

100

1.00 (1.00–1.00)

>1.9 (>14.3)

402

2.1–7.8 (14.4–58.7)

4.36 ± 1.11 (33.1 ± 8.4)

Maximal

≤2.3 (≤17.3)

293

0.7–2.3 (5.3–17.3)

1.58 ± 0.34 (12.1 ± 2.6

100

87

91

100

0.99 (0.99–1.00)

>2.3 (>17.3)

444

2.4–10.7 (18.1–80.5)

5.12 ± 1.57 (38.4 ± 11.9)

Final

≤1.7 (≤12.8)

335

0.2–1.7 (1.7–12.8)

0.98 ± 0.33 (7.4 ± 3.2)

100

99

99

100

1.00 (1.00–1.00)

>1.7 (>12.8)

402

1.9–6.6 (14.3–49.7)

0.98 ± 0.33 (27.8 ± 7.2)


AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, return of spontaneous circulation; SD, standard deviation

Kolar et al. Critical Care 2008 12:R115   doi:10.1186/cc7009

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