Table 3 |
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|
Performance of various values of PetCO2 and duration of CPR for predicting ROSC in all patients with cardiac arrest |
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|
PetCO2 |
Cut-off (kPa [mmHg]) |
n |
Min-max (kPa [mmHg]) |
Mean ± SD (kPa [mmHg]) |
Sensitivity (%) |
Specificity (%) |
PPV (%) |
NPV (%) |
AUROC (95% CI) |
|
|
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|
Initial |
≤1.3 (≤10) |
168 |
0.0–1.3 (0.0–10) |
0.68 ± 0.34 (5.1 ± 2.5) |
100 |
50 |
71 |
100 |
0.68 (0.63–0.72) |
|
>1.3 (>10) |
569 |
1.4–8.7 (10.1–65.4) |
3.52 ± 1.93 (26.3 ± 14.5) |
||||||
|
0 to 10 minutes |
≤1.6 (≤12.1) |
306 |
0.3–1.6 (2.3–12.1) |
0.96 ± 0.34 (7.2 ± 2.6) |
100 |
91 |
93 |
100 |
0.99 (0.99–1.00) |
|
>1.6 (>12.1) |
431 |
1.7–5.6 (12.2–42.1) |
2.79 ± 0.82 (20.9 ± 0.8) |
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|
10 minutes |
≤1.3 (≤9.8) |
202 |
0.3–1.3 (2.3–9.8) |
0.85 ± 0.31 (6.4 ± 2.1) |
100 |
60 |
75 |
100 |
0.99 (0.98–0.99) |
|
>1.3 (>9.8) |
535 |
1.4–7.2 (9.9–54.2) |
2.89 ± 1.09 (21.7 ± 8.2) |
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|
11–15 minutes |
≤1.7 (≤12.8) |
333 |
0.4–1.7 (3.1–12.8) |
0.99 ± 0.30 (7.6 ± 2.2) |
100 |
99 |
99 |
100 |
1.00 (0.99–1.00) |
|
>1.7 (>12.8) |
404 |
1.8–5.5 (12.8–41.4) |
3.19 ± 0.77 (23.9 ± 4.8) |
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|
15 minutes |
≤1.8 (≤13.6) |
328 |
0.2–1.8 (1.5–13.5) |
1.11 ± 0.39 (8.4 ± 2.8) |
100 |
98 |
98 |
100 |
0.99 (0.99–1.00) |
|
>1.8 (>13.6) |
409 |
1.9–7.7 (13.6–57.9) |
3.65 ± 0.98 (27.8 ± 7.4) |
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|
20 minutes |
≤1.9 (≤14.3) |
335 |
0.3–1.9 (2.3–14.3) |
0.92 ± 0.29 (6.8 ± 2.1) |
100 |
100 |
100 |
100 |
1.00 (1.00–1.00) |
|
>1.9 (>14.3) |
402 |
2.1–7.8 (14.4–58.7) |
4.36 ± 1.11 (33.1 ± 8.4) |
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|
Maximal |
≤2.3 (≤17.3) |
293 |
0.7–2.3 (5.3–17.3) |
1.58 ± 0.34 (12.1 ± 2.6 |
100 |
87 |
91 |
100 |
0.99 (0.99–1.00) |
|
>2.3 (>17.3) |
444 |
2.4–10.7 (18.1–80.5) |
5.12 ± 1.57 (38.4 ± 11.9) |
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|
Final |
≤1.7 (≤12.8) |
335 |
0.2–1.7 (1.7–12.8) |
0.98 ± 0.33 (7.4 ± 3.2) |
100 |
99 |
99 |
100 |
1.00 (1.00–1.00) |
|
>1.7 (>12.8) |
402 |
1.9–6.6 (14.3–49.7) |
0.98 ± 0.33 (27.8 ± 7.2) |
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|
|
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|
AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, return of spontaneous circulation; SD, standard deviation |
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|
Kolar et al. Critical Care 2008 12:R115 doi:10.1186/cc7009 |
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