Table 7

Performance of various values of PetCO2 and duration of CPR for prediction of ROSC in patients with shockable initial rhythm in cardiac arrest

PetCO2

Cut-off (kPa [mmHg])

n

Min-max (kPa [mmHg])

Mean ± SD (kPa [mmHg])

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

AUROC (95% CI)


Initial

≤1.3 (10)

71

0.0–1.3 (0.0–10)

0.69 ± 0.3 (5.2 ± 2.6)

100

76

91

100

0.93 (0.86–0.97)

>1.3 (10)

233

1.4–8.7 (10.1–65.4)

2.59 ± 1.08 (19.6 ± 8.3)

0–10 minute (average)

≤1.6 (12.1)

86

0.3–1.6 (2.8–12.1)

0.96 ± 0.33 (7.22 ± 3.1)

100

92

97

100

0.99 (0.99–1.00)

>1.6 (12.1)

218

1.7–4.8 (12.2–39.1)

2.83 ± 0.77 (21.1 ± 5.8)

10 minute

≤1.5 (11.3)

72

0.3–1.5 (2.6–11.3)

0.96 ± 0.37 (7.2 ± 2.9)

100

77

91

100

0.99 (0.98–0.99)

>1.5 (11.3)

232

1.6–5.8 (11.4–43.6)

3.17 ± 0.96 (24.1 ± 7.3)

11–15 minute (average)

≤1.6 (12.1)

93

0.4–1.6 (3.7–12.1)

0.99 ± 0.28 (7.5 ± 2.1)

100

100

100

100

1.00 (1.00–1.00)

>1.6 (12.1)

211

1.8–5.5 (13.5–41.4)

3.22 ± 0.74 (24.1 ± 8.3)

15 minute

≤1.8 (13.5)

92

0.2–1.8 (1.6–13.5)

1.11 ± 0.39 (7.9 ± 2.9)

100

99

100

100

1.00 (1.00–1.00)

>1.8 (13.5)

212

1.9–7.7 (13.6–59.3)

3.71 ± 0.99 (27.8 ± 7.3)

20 minute

≤1.5 (11.3)

93

0.3–1.5 (2.8–11.3)

0.95 ± 0.26 (7.3 ± 2.2)

100

100

100

100

1.00 (1.00–1.00)

>1.5 (11.3)

211

2.1–7.3 (11.4–54.9)

4.33 ± 1.11 (32.3 ± 7.9)

Max

≤2.3 (17.3)

83

0.7–2.3 (5.26–17.3)

1.56 ± 0.34 (13.2 ± 3.4)

100

89

95

100

0.99 (0.90–1.00)

>2.3 (17.3)

221

2.4–10.6 (17.4–79.7)

5.23 ± 1.5 (39.2 ± 11.3)

Final

≤1.5 (11.3)

93

0.3–1.5 (2.6–11.3

1.0 ± 0.32 (7.5 ± 1.9)

100

100

100

100

1.00 (1.00–1.00)

>1.5 (11.3)

211

1.9–6.3 (11.3–47.4)

3.69 ± 0.94 (27.8 ± 7.1)


'Shockable' was defined as ventricular fibrillation or tachycardia. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, restoration of spontaneous circulation; SD, standard deviation.

Kolar et al. Critical Care 2008 12:R115   doi:10.1186/cc7009

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