Table 8 |
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|
Performance of various values of PetCO2 and duration of CPR for prediction of ROSC in patients with nonshockable initial rhythm in cardiac arrest |
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|
PetCO2 |
Cut-off (kPa [mmHg]) |
n |
Min-max (kPa [mmHg]) |
Mean ± SD (kPa [mmHg]) |
Sensitivity (%) |
Specificity (%) |
PPV (%) |
NPV (%) |
AUROC (95% CI) |
|
|
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|
Initial |
≤1.3 (10) |
97 |
0.0–1.3 (0.0–10) |
0.66 ± 0.32 (5.1 ± 2.3) |
100 |
40 |
57 |
100 |
0.61 (0.56–0.67) |
|
>1.3 (10) |
336 |
1.4–8.4 (10.1–63.2) |
4.17 ± 2.2 (30.8 ± 15.8) |
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|
0–10 minute (average) |
≤1.6 (12.1) |
220 |
0.4–1.6 (3.4–12.1) |
0.97 ± 0.34 (7.3 ± 2.2) |
100 |
91 |
90 |
100 |
0.99 (0.98–0.99) |
|
>1.6 (12.1) |
213 |
1.7–5.6 (12.2–42.1) |
2.74 ± 0.87 (20.6 ± 6.7) |
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|
10 minute |
≤1.3 (11) |
147 |
0.3–1.3 (3.6–11) |
0.86 ± 0.32 (6.9 ± 2.1) |
100 |
61 |
67 |
100 |
0.98 (0.97–0.99) |
|
>1.3 (11) |
286 |
1.4–7.2 (11.1–54.2) |
2.74 ± 1.14 (21.1 ± 7.9) |
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|
11–15 minute (average) |
≤1.7 (12.8) |
240 |
0.4–1.7 (3.7–12.8) |
0.99 ± 0.31 (7.3 ± 2.6) |
100 |
99 |
99 |
100 |
1.00 (0.99–1.00) |
|
>1.7 (12.8) |
193 |
1.9–5.1 (12.9–38.4) |
3.15 ± 0.79 (24.1 ± 7.1) |
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|
15 minute |
≤1.8 (13.5) |
236 |
0.3–1.8 (2.3–13.5) |
1.11 ± 0.39 (7.7 ± 3.3) |
100 |
98 |
97 |
100 |
0.99 (0.99–1.00) |
|
>1.8 (13.5) |
197 |
1.9–6.1 (13.6–45.9) |
3.58 ± 0.97 (27.1 ± 7.4) |
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|
20 minute |
≤1.9 (14.3) |
242 |
0.3–1.9 (2.2–14.3) |
0.91 ± 0.29 (7.3 ± 2.4) |
100 |
100 |
100 |
100 |
1.00 (1.00–1.00) |
|
>1.9 (14.3) |
191 |
2.1–7.8 (14.4–58.7) |
4.38 ± 1.17 (33.1 ± 7.6) |
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|
Max |
≤2.3 (17.3) |
210 |
0.8–2.3 (6.7–17.3) |
1.59 ± 0.35 (13.2 ± 3.4) |
100 |
87 |
86 |
100 |
1.00 (1.00–1.00) |
|
>2.3 (17.3) |
223 |
2.4–10.7 (17.4–80.5) |
5.0 ± 1.61 (37.6 ± 15.8) |
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|
Final |
≤1.6 (12.3) |
239 |
0.2–1.6 (1.8–12.3) |
0.97 ± 0.33 (7.2 ± 2.8) |
100 |
99 |
98 |
100 |
1.00 (1.00–1.00) |
|
>1.6 (12.3) |
194 |
1.0–6.6 (12.4–49.6) |
3.59 ± 0.98 (27.1 ± 7.4) |
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|
|
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|
'Nonshockable' was defined as asystole or pulseless electrical activity. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, restoration of spontaneous circulation; SD, standard deviation |
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|
Kolar et al. Critical Care 2008 12:R115 doi:10.1186/cc7009 |
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