Table 9 |
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|
Performance of various values of PetCO2 and duration of CPR for prediction of survival in patients with shockable initial rhythm in cardiac arrest |
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|
PetCO2 |
Cut-off (kPa [mmHg]) |
n |
Min-max (kPa [mmHg]) |
Mean ± SD (kPa [mmHg]) |
Sensitivity (%) |
Specificity (%) |
PPV (%) |
NPV (%) |
AUROC (95% CI) |
|
|
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|
Initial |
≤1.3 (10) |
71 |
0.0–10 (0.0–1.3) |
5.3 ± 1.9 (0.69 ± 0.35) |
100 |
34 |
40 |
100 |
0.73 (0.67–0.78) |
|
>1.3 (10 |
233 |
10.1–65.4 (1.4–8.7) |
19.5 ± 6.8 (2.59 ± 1.07) |
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|
0–10 minute (average) |
≤1.7 (12.8) |
91 |
0.3–1.7 (2,5–12.8) |
0.99 ± 0.36 (7.5 ± 2.1) |
100 |
43 |
44 |
100 |
0.82 (0.78–0.87) |
|
>1.7 (12.8) |
213 |
1.8–4.8 (12.9–36.1) |
2.86 ± 0.76 (21.8 ± 5.2) |
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|
10 minute |
≤1.6 (12.1) |
82 |
0.3–1.6 (2.3–12.1) |
1.04 ± 0.41 (7.6 ± 3.4) |
100 |
39 |
42 |
100 |
0.82 (0.78–0.87) |
|
>1.6 (12.1) |
222 |
1.7–5.8 (12.2–43.6) |
3.24 ± 0.93 (24.1 ± 7.1) |
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|
11–15 minute (average) |
≤1.6 (12.1) |
93 |
0.4–1.6 (3.3–12.2) |
0.99 ± 0.28 (7.4 ± 2.3) |
100 |
44 |
45 |
100 |
0.78 (0.73–0.83) |
|
>1.6 (12.1) |
211 |
1.8–5.5 (12.3–41.4) |
3.22 ± 0.74 (24.4 ± 4.9) |
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|
15 minute |
≤1.9 (14.3) |
94 |
0.2–1.9 (1.9–14.3) |
1.25 ± 0.41 (7.9 ± 2.9) |
100 |
45 |
45 |
100 |
0.78 (0.73–0.83) |
|
>1.9 (14.3) |
210 |
2.0–7.7 (14.4–57.9) |
3.73 ± 0.98 (27.8 ± 7.1) |
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|
20 minute |
≤1.5 (11.3) |
93 |
0.3–1.5 (2.8–11.3) |
0.95 ± 0.26 (7.2 ± 2.1) |
100 |
44 |
45 |
100 |
0.78 (0.72–0.83) |
|
>1.5 (11.3) |
211 |
2.1–7.3 (11.4–54.9) |
4.33 ± 1.11 (32.3 ± 7.8) |
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|
Max |
≤2.5 (18.8) |
89 |
0.7–2.5 (0.7–18.8) |
1.62 ± 0.39 (12.4 ± 3.3) |
100 |
42 |
44 |
100 |
0.81 (0.76–0.86) |
|
>2.5 (18.8) |
215 |
2.6–10.6 (18.9–79.7) |
5.3 ± 1.48 (39.9 ± 11.5) |
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|
Final |
≤1.5 (11.3) |
93 |
0.3–1.5 (2.7–11.3) |
1.0 ± 0.32 (7.5 ± 3.1) |
100 |
44 |
45 |
100 |
0.78 (0.73–0.83) |
|
>1.5 (11.3) |
211 |
1.9–6.3 (11.4–47.4) |
3.69 ± 0.94 (27.8 ± 6.9) |
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|
|
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|
'Shockable' was defined as ventricular fibrillation or tachycardia. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; CPR, cardiopulmonary resuscitation; NPV, negative predictive value; PetCO2, partial pressure of end-tidal carbon dioxide; PPV, positive predictive value; ROSC, restoration of spontaneous circulation; SD, standard deviation. |
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|
Kolar et al. Critical Care 2008 12:R115 doi:10.1186/cc7009 |
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