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Incidence, mortality, and criteria for acute kidney injury in patients with burns |
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| Reference |
Year |
Years of study; population |
AKI |
AKI mortality |
Criterion of AKI |
|
|
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| Davies, et al. [8] |
1979 |
1958–1979; >1,064 patients admitted |
28 (<2.6%) |
24 (86%) |
Renal replacement therapy |
| Davies, et al. [9] |
1994 |
1991; 18 burn units |
15 (<1%) |
12 (80%) |
Renal replacement therapy |
| Leblanc, et al. [10] |
1997 |
1987–1994; 970 patients admitted |
16 (1.6%) |
13 (82%) |
Renal replacement therapy |
| Holm, et al. [11] |
1999 |
1994–1998; 328 patients, 34% TBSA% |
48 (15%) |
41 (85%) |
Renal replacement therapy |
| Tremblay, et al. [12] |
2000 |
1995–1998; 353 patients admitted |
12 (3.4%) |
6 (50%) |
Renal replacement therapy |
| Schiavon, et al. [13] |
1988 |
1988; 20 patients, 44% TBSA% |
4 (20%) |
4 (100%) |
Serum creatinine raised >133 μmol/L above value on admission |
| 0 |
Renal replacement therapy |
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| Saffle, et al. [7] |
1993 |
1987–1990; 529 patients, 16% TBSA% |
50 (10%) |
23 (46%) |
Thermal Injury Organ Failure Score (moderate: serum creatinine >222 μmol/L) |
| 4 (0.8%) |
4 (100%) |
Renal replacement therapy |
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| Sheridan, et al. [14] |
1998 |
1989–1994; 56 patients who died |
37 (68%) |
- |
Serum BUN ≥100 and creatinine ≥3.5 or urine output ≤500 mL/day |
| Jeschke, et al. [15] |
1998 |
1966–1997; 5,000 children admitted |
60 (1.2%) |
44 (73%) |
Oliguria (<0.5 mL/kg per hour for >36 hours), serum urea nitrogen/creatinine ratio <20, serum creatinine >177 μmol/L |
| 34 (0.7) |
28 (82%) |
Renal replacement therapy |
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| Chrysopoulo, et al. [16] |
1999 |
1981–1998; 1,404 patients, TBSA% >30% |
76 (5.4%) |
67 (88%) |
Three of these four: oliguria (<350 mL/36 hours), BUN/creatinine ratio <20, serum creatinine >177 μmol/L, and dialysis |
| 67 (4.8%) |
61 (91%) |
Renal replacement therapy |
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| Kim, et al. [17] |
2003 |
2000; 147 patients, 60% TBSA% |
28 (19%) |
28 (100%) |
Serum creatinine >177 μmol/L |
| 3 (2.0%) |
3 (100%) |
Renal replacement therapy |
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| Mustonen and Vuola [22] |
2008 |
1988–2001; 238 patients, 31% TBSA% |
93 (39.1%) |
41 (44%) |
Serum creatinine >120 μmol/L |
| 32 (13%) |
20 (62%) |
Renal replacement therapy |
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| Cumming, et al. [6] |
2001 |
1998–1999; 85 patients, 30% TBSA% |
3 (3.5%) |
MODS (3–4: serum creatinine >350 μmol/L) |
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| Cooper, et al. [18] |
2006 |
1999–2001; 42 patients, 35% TBSA% |
3 (7.1%) |
MODS (3–4: serum creatinine >350 μmol/L) or oliguria |
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| Coca, et al. [19] |
2007 |
1998–2003; 304 patients, 27% TBSA% |
81 (27%) |
23 (28%) |
RIFLE |
| (73%) |
Renal replacement therapy |
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| Lopes, et al. [20] |
2007 |
2004–2006; 126 patients, 24% TBSA% |
45 (36%) |
21 (47%) |
RIFLE |
| 11 (8.7%) |
Renal replacement therapy |
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The table shows number of patients who had acute kidney injury (AKI) according to the criteria in the rightmost column; the percentage is the incidence of AKI among the study population. AKI mortality is the number of patients who died among those with AKI, with the percentage referring to mortality among the AKI patients. When available, incidence and outcome of renal replacement therapy are shown in the table, together with the result from the primary AKI criteria. Percentage burned of total body surface area (TBSA%) is the mean of the study group. When a TBSA% limit for inclusion was reported instead, it is shown in this table as 'TBSA% >%'. BUN, blood urea nitrogen; MODS, Multiple Organ Dysfunction Score; RIFLE, the increasing severity classes Risk, Injury, and Failure and the two outcome classes Loss, and End-stage renal disease. | |||||
Steinvall et al. Critical Care 2008 12:R124 doi:10.1186/cc7032 |
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