Table 3 |
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|
Haemodynamic parameters of endotoxaemic rats. art = arterial; BE = base excess; ENHA = erythro-9-[2-hydroxyl-3-nonyl]-adenine; LPS = lipopolysaccharide; pCO2 = partial pressure of carbon dioxide; pHCO3- = bicarbonate; pO2 = partial pressure of oxygen; SO2 = oxygen saturation. Data are mean ± standard error of the mean. |
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|
Parameter |
Group |
Time (minutes) |
||
|
|
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|
0 |
60 |
120 |
||
|
|
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|
art. SO2 |
Control |
94.5 ± 0.7 |
97.2 ± 0.5 |
95.5 ± 1.0 |
|
|
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|
LPS |
96.3 ± 0.8 |
97.4 ± 0.5 |
97.2 ± 0.3 |
|
|
|
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|
LPS + EHNA |
94.4 ± 0.5 |
92.4 ± 4.3 |
91.3 ± 5.6 |
|
|
|
||||
|
art. PO2 |
control |
83.4 ± 4.4 |
86.7 ± 3.7 |
88.3 ± 2.8 |
|
|
||||
|
LPS |
95.1 ± 9.5 |
107.1 ± 9.4 |
99.7 ± 4.2 |
|
|
|
||||
|
LPS + EHNA |
75.7 ± 2.3 |
89.5 ± 5.3 |
86.6 ± 6.9 |
|
|
|
||||
|
art. PCO2 |
control |
47.2 ± 1.4 |
41.3 ± 1.7 |
40.2 ± 1.1 |
|
|
||||
|
LPS |
42.8 ± 1.6 |
37.1 ± 1 |
35.0 ± 0.8 |
|
|
|
||||
|
LPS + EHNA |
49.5 ± 1 |
35.8 ± 3.9 |
34.0 ± 2.4 |
|
|
|
||||
|
art. HCO3 - |
control |
26.9 ± 0.5 |
24.5 ± 1.0 |
24.1 ± 0.5 |
|
|
||||
|
LPS |
25.3 ± 1.0 |
22.8 ± 0.6 |
18.6 ± 1.0 |
|
|
|
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|
LPS + EHNA |
28.2 ± 0.5 |
21.3 ± 3.4 |
18.7 2.5 |
|
|
|
||||
|
art. PH |
control |
7.37 ± 0.01 |
7.40 ± 0.01 |
7.39 ± 0.01 |
|
|
||||
|
LPS |
7.38 ± 0.01 |
7.40 ± 0.01 |
7.35 ± 0.02 |
|
|
|
||||
|
LPS + EHNA |
7.36 ± 0.01 |
7.28 ± 0.12 |
7.31 ± 0.07 |
|
|
|
||||
|
art. BE |
control |
1.4 ± 0.6 |
0.2 ± 1.0 |
0.2 ± 0.4 |
|
|
||||
|
LPS |
0.5 ± 0.9 |
-1.1 ± 0.7 |
-5.8 ± 1.3 |
|
|
|
||||
|
LPS + EHNA |
2.4 ± 0.6 |
-5.3 ± 5.9 |
-6.6 ± 3.7 |
|
|
|
||||
|
Kayhan et al. Critical Care 2008 12:R125 doi:10.1186/cc7033 |
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