Critical Care

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Commentary

Acute kidney injury in burns: a story of volume and inflammation

Kirsten Colpaert and Eric A Hoste*

Author Affiliations

Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium

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Critical Care 2008, 12:192 doi:10.1186/cc7106

Published: 25 November 2008

Abstract

Acute kidney injury occurs in approximately one-quarter to one-third of patients with major burn injury. Apart from the usual suspects – such as older age, severity of burn injury, sepsis and multiple organ dysfunction – volume overload probably has an important role in the pathogenesis of acute kidney injury.