Critical Care

official impact factor 4.60

Commentary

The severity of sepsis: yet another factor influencing glycemic control

James S Krinsley

Author Affiliations

Stamford Hospital, 190 West Broad Street, Stamford, CT 06902, USA

Critical Care 2008, 12:194 doi:10.1186/cc7111

Published: 25 November 2008

Abstract

The present commentary provides a brief overview of the evolving literature on glycemic management in critically ill patients. Recent interventional studies have been plagued by high rates of severe hypoglycemia among patients, particularly those with sepsis. The investigation by Waeschle and colleagues adds to our knowledge about the relationship between the severity of sepsis and glycemic dysregulation. The severity of sepsis is shown to correlate with the risk of sustaining hyperglycemia as well as critical hypoglycemia.