|
Drugs recognized to exhibit altered nonrenal clearance in acute kidney injury in clinical studies |
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| Drug |
Normal renal function |
Acute kidney injury |
End-stage renal disease |
|
|
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| Imipenem |
130 ml/minute [55-58] |
90 to 95 ml/minute [8,59] |
50 ml/minute [8,60,61] |
| Meropenem |
45 to 60 ml/minute [62-64] |
40 to 60 ml/minute [65,66] |
30 to 35 ml/minute [63,64] |
| Vancomycin |
40 ml/minute [67] |
15 ml/minute [7] |
5 ml/minute [68,69] |
Vilay et al. Critical Care 2008 12:235 doi:10.1186/cc7093 |
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