Table 2

Admission and outcome parameters of study patients


IAH
FI
Admission parameters
 Total
 Absent
 Present
 P
 Absent
 Present
 P
Number of patients [%]
 264 [100.0]
 192 [72.3]
 72 [27.3]
110 [41.7]
 154 [58.3]
Male sex (n [%])
 166 [62.9]
 117 [60.9]
 49 [68.1]
 0.178
 60 [54.5]
 106 [68.8]
 0.013
Age (years)
 53.8 ± 20.0
 52.3 ± 21.0
 57.8 ± 16.8
 0.047
 48.6 ± 21.0
 57.5 ± 18.5
 < 0.001
Diabetes (n [%])
 35 [13.3]
 26 [13.5]
 9 [12.5]
 0.502
 11 [10.0]
 24 [15.6]
 0.128
Readmission (n [%])
 8 [3.0]
 6 [3.1]
 2 [2.8]
 0.622
 2 [1.8]
 6 [3.9]
 0.287
Sedation (n [%])
 243 [92.0]
 174 [90.6]
 69 [95.8]
 0.125
 98 [89.1]
 145 [94.2]
 0.103
Vasoactive/inotrope (n [%])
 200 [75.8]
 136 [70.8]
 64 [88.9]
 0.001
 67 [60.9]
 133 [86.4]
 < 0.001
Surgical profile (n [%])
 175 [66.3]
 122 [63.5]
 53 [73.7]
 0.080
 67 [60.9]
 108 [70.1]
 0.077
Laparatomy (n [%])
 60 [23.3]
 21 [15.6]
 31 [43.7]
 < 0.001
 9 [8.4]
 51 [34.0]
 < 0.001
Enteral feeding (n [%])
 49 [18.6]
 42 [21.9]
 7 [9.7]
 0.015
 25 [22.7]
 24 [15.6]
 0.095
APACHE II score (points)
 14.2 ± 7.7
 13.5 ± 7.6
 16.0 ± 7.7
 0.016
 11.8 ± 7.3
 15.8 ± 7.6
 < 0.001
BMI (kg/m2)
 27.6 ± 13.1
 25.4 ± 4.6
 33.1 ± 22.2
 < 0.001
 25.8 ± 5.6
 28.9 ± 16.4
 0.080
SOFA score (points)
 7.0 ± 4.2
 6.3 ± 4.2
 8.9 ± 3.6
 < 0.001
 5.3 ± 4.2
 8.2 ± 3.8
 < 0.001
Fluid gain in first 24 hours (l)
 2.4 ± 3.6
 2.0 ± 2.4
 3.6 ± 5.5
 0.001
 1.7 ± 2.4
 2.9 ± 4.2
 0.007
MAP (mmHg)
 81.5 ± 15.9
 82.1 ± 16.4
 80.5 ± 15.0
 0.512
 82.1 ± 15.8
 81.3 ± 16.1
 0.758
IAP (mmHg)
 8.5 ± 4.7
 6.5 ± 3.8
 12.1 ± 4.0
 < 0.001
 6.3 ± 4.0
 9.5 ± 4.6
 < 0.001
CVP (mmHg)
 11.6 ± 5.7
 10.3 ± 4.9
 14.3 ± 6.3
 < 0.001
 10.4 ± 5.1
 12.2 ± 5.9
 0.031
PIP (cmH2O)
 23.9 ± 6.2
 22.6 ± 6.0
 27.2 ± 5.2
 < 0.001
 22.5 ± 6.5
 24.8 ± 5.7
 0.006
PEEP (cmH2O)
 9.2 ± 4.2
 8.5 ± 4.1
 11.2 ± 3.7
 < 0.001
 7.8 ± 4.1
 10.2 ± 3.9
 < 0.001
Lactate (mmol/l)
 4.6 ± 5.4
 4.4 ± 4.6
 4.9 ± 6.9
 0.519
 4.4 ± 4.9
 4.7 ± 5.7
 0.741
FI (n [%])
 124 [47.0]
 69 [35.9]
 55 [76.4]
 < 0.001
 -
 -
IAH (n [%])
 42 [15.9]
 -
 -
3 [2.7]
 39 [25.3]
 < 0.001
Gastrointestinal failure (FI+IAH; n [%])
 36 [13.6]
 -
 36 [50.0]
-
 36 [23.4]
Outcome parameters






     MV (days)
 7.4 ± 11.9
 4.3 ± 6.1
 15.5 ± 18.0
 < 0.001
 3.6 ± 5.9
 10.0 ± 14.1
 < 0.001
     ICU stay (days)
 8.8 ± 12.8
 5.6 ± 7.3
 17.5 ± 19.0
 < 0.001
 4.8 ± 6.9
 11.7 ± 15.1
 < 0.001
     ICU mortality (n [%])
 39 [14.8]
 21 [10.9]
 18 [25.0]
 0.005
 7 [6.4]
 32 [20.8]
 0.001
     28-day mortality (n [%])
 54 [20.5]
 36 [18.8]
 18 [25.0]
 0.171
 13 [11.8]
 41 [26.6]
 < 0.001
     90-day mortality (n [%])
 75 [28.4]
 48 [25.0]
 27 [37.5]
 0.033
 17 [15.5]
 58 [37.7]
 0.002

The values are presented as mean ± standard deviation, if not stated otherwise. APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; CVP, central venous pressure; FI, food intolerance; IAH, intra-abdominal hypertension; IAP, intra-abdominal pressure; ICU, intensive care unit; MAP, mean arterial pressure; MV, mechanical ventilation; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure; SOFA, Sequential Organ Failure Assessment.

Reintam et al. Critical Care 2008 12:435   doi:10.1186/cc7135