Table 1 |
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Patient characteristics and factors associated with cardiac dysfunction at intensive care unit admission |
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Variables |
All patients |
Cardiac dysfunction |
No cardiac dysfunction |
Odds ratio |
95% CI |
P value |
|
|
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|
n = 198 |
n = 102 |
n = 96 |
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|
|
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|
|
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Male gender |
130 (65.7%) |
70 (68.6%) |
60 (62.5%) |
1.31 |
0.72–2.36 |
0.36 |
|
|
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|
|
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Age |
67 (53–77) |
73.5 (60–79) |
58.5 (45–72) |
1.04 |
1.02–1.06 |
< 0.0001 |
|
< 50 years |
31 (15.7%) |
8 (7.8%) |
23 (24.0%) |
0.27 |
0.11–0.64 |
0.003 |
|
50–70 years |
78 (39.4%) |
34 (33.3%) |
44 (45.8%) |
0.59 |
0.33–1.05 |
0.07 |
|
> 70 years |
89 (44.9%) |
60 (58.8%) |
29 (30.2%) |
3.30 |
1.83–5.94 |
< 0.0001 |
|
|
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|
|
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|
SAPS II at ICU admission [9] |
37 (26–58) |
45 (30–65) |
32 (22–50) |
1.03 |
1.01–1.04 |
0.0001 |
|
|
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|
OSF score at ICU admission [8] |
1 (0–2) |
1 (0–2) |
1 (0–1) |
1.62 |
1.21–2.16 |
0.0001 |
|
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|
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Comorbidities |
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|
|
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Chronic cardiac failure |
42 (21.2%) |
28 (27.5%) |
14 (14.6%) |
2.22 |
1.08–4.53 |
0.29 |
|
|
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|
Chronic renal failure |
101 (51.0%) |
64 (62.7%) |
37 (34.7%) |
3.01 |
1.65–5.48 |
0.0003 |
|
|
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|
Creatinine clearance, mL/minute |
48 (25–76) |
36 (11–65) |
50 (37–96) |
0.98 |
0.98–0.99 |
0.0006 |
|
|
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|
|
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Organ failure according to OSF score |
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|
|
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|
Cardiovascular |
50 (25.2%) |
36 (35.3%) |
14 (14.6%) |
3.74 |
1.57–6.39 |
0.001 |
|
Respiratory |
63 (31.8%) |
38 (37.2%) |
25 (26.0%) |
1.66 |
0.90–3.07 |
0.10 |
|
Renal |
50 (25.2%) |
34 (33.3%) |
16 (16.7%) |
2.48 |
1.26–4.89 |
0.008 |
|
Neurological |
43 (21.7%) |
27 (26.5%) |
16 (16.7%) |
1.78 |
0.88–3.57 |
0.10 |
|
Hepatic |
8 (4.0%) |
4 (3.9%) |
4 (3.1%) |
0.93 |
0.22–3.82 |
0.91 |
|
|
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|
|
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|
Clinically documented infection |
73 (36.9%) |
38 (37.2) |
35 (36.4%) |
0.99 |
0.55–1.79 |
0.98 |
|
|
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|
|
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|
NT-proBNP per 100 ng/L |
26.3 (4.7–73.0) |
57.2 (14.3–157.0) |
8.5 (1.9–35.6) |
1.01 |
1.01–1.02 |
< 0.0001 |
|
|
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|
Troponin (ng/mL) |
0.10 (0.02–0.44) |
0.16 (0.05–1.1) |
0.06 (0.01–0.21) |
1.39 |
1.03–1.88 |
0.03 |
|
|
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|
ECG modifications |
92 (46.5%) |
75 (73.5%) |
17 (17.7%) |
12.90 |
6.51–25.59 |
< 0.0001 |
|
|
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|
C-reactive protein (mg/L) |
186 (78–332) |
234 (84–370) |
156 (74–223) |
1.003 |
0.98–1.01 |
0.3 |
|
|
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|
|
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|
Inotropic agents |
43 (21.7%) |
40 (39.2%) |
3 (3.1%) |
20 |
5.92–67.51 |
< 0.0001 |
|
Vasopressive agents |
52 (26.3%) |
37 (36.3%) |
15 (15.6%) |
3.74 |
1.55–6.86 |
0.0013 |
|
|
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|
|
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|
Length of ICU stay, days |
3 (1–8) |
4 (1–10) |
3 (1–6) |
1.17 |
0.98–1.52 |
0.34 |
|
|
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|
Length of hospital stay, days |
10 (3–21) |
11 (4.5–23.5) |
10 (3–20) |
1.01 |
0.99–1.01 |
0.39 |
|
|
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|
ICU mortality |
47 (23.7%) |
35 (34.3%) |
12 (12.5%) |
3.65 |
1.76–7.59 |
0.0005 |
|
|
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|
Hospital mortality |
72 (36.3%) |
52 (51%) |
20 (20.8%) |
3.95 |
2.1–7.4 |
< 0.0001 |
|
|
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|
Data are presented as medians and quartiles (interquartile ranges) or as numbers (percentages). CI, confidence interval; ECG, electrocardiogram; ICU, intensive care unit; NT-proBNP, N-terminal-pro-B-type natriuretic peptide; OSF, organ system failure [8]; SAPS II, Simplified Acute Physiology Score II [9]. |
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|
Coquet et al. Critical Care 2008 12:R137 doi:10.1186/cc7110 |
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