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Hypoglycaemia quality indicator subgroups |
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| Indicators |
Description |
Reference |
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| Hypoglycaemic events |
Reported thresholdsa for defining a BGL as hypoglycaemic event: • <40 [8,10,17-19,30,35,43]; • ≤ 40 [26]; • <45 [44,54]; • <50 [31,49,50]; • <54 [34]; • <57 [32]; • <60 [8,11,45,52,55]; • ≤ 60 [16,21]; • <63 [23]; • <65 [25]; • <70 [9,17,22,27,28,57]; • <72 [20]; or • threshold was not reported [48] Represented as: • percentage and number of measurements and/or patients with hypoglycaemic event during the trial, or normalized for duration of therapy [16]; • mean or median of events per patient-day [57]; • mean of events per patient [27]; • patients with at least one event per day [22]; or • in three studies, hypoglycaemic events did not occur and therefore were not reported [32,48,54] |
31 articles [8-11,16-23,25-28,30-32,34,35,43-45,48-50,52,54,55,57] |
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| Severe or marked hypoglycaemic events |
Reported threshold for defining a BGL as severe hypoglycaemic event: • <40 [15,20,25,29,33,42,46,47,51,56]; • ≤ 40 [12,13,16]; • <48 [24]; or • in one study clinical finding defined as severe hypoglycaemia [8] Represented as: • percentage and number of measurements and/or patients with severe hypoglycaemic event; • mean or median of events per patient-day [29]; • In two studies severe hypoglycaemic events did not occur and therefore not reported [47,56] |
15 articles [8,12,13,15,16,20,24,25,29,33,42,46,47,51,56] |
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| Need for dextrose injection |
Reported threshold for dextrose injection: • <45 [29]; • <54 [44]; • <60 [53]; • <63 [23]; • <65 [25]; or • threshold was not reported [21,56] Represented as: • percentage and number of patient with dextrose injection [21,23,29,44,53,56]; or • percentage and number of dextrose injections [25] |
7 articles [21,23,25,29,44,53,56] |
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| Mild or moderate hypoglycaemic events |
Reported threshold for defining an BGL as severe hypoglycaemic event: • 40–59 [42]; • <60 [46]; • 40–60 [51]; • <63 [15] Represented as percentage and number of measurements and/or patients with a moderate hypoglycaemic event |
4 articles [15,42,46,51] |
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| Hypoglycaemia duration |
Represented cumulatively [29], as median [24] and per patient [21] |
3 articles [21,24,29] |
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| Time until next in predefined range after hypoglycaemia |
Represent as mean [8,49] or median [31] time |
3 articles [8,31,49] |
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| Duration of stopping IIT because of hypoglycaemia |
Represented as median of percentage of time per patient |
2 articles [29,33] |
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| Next BGL after hypoglycaemia |
Represented as mean BGL |
2 articles [8,49] |
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| Time until reaction to hypoglycaemic event |
Represented as maximum time till hypoglycaemia recognition [8] or mean time till IIT adjustment after hypoglycaemic event [28] |
2 articles [8,28] |
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| Time from starting IIT until first hypoglycaemia |
Represented as mean time |
1 article [19] |
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| Time till next BGL after hypoglycaemia |
Represented as mean time |
1 article [49] |
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aUnit of all BGL thresholds is mg/dl. BGL, blood glucose level; IIT, intensive insulin therapy. | ||
Eslami et al. Critical Care 2008 12:R139 doi:10.1186/cc7114 |
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