|
Multivariable regression analysis of factors associated with the involvement of MDR pathogens in VAP (n = 192). |
||||
| Predictor |
Parameter estimate |
OR |
CI |
p value |
|
|
||||
| Enter method |
||||
| Age |
0.01 |
1.01 |
0.99 to 1.03 |
0.23 |
| Charlson index |
0.85 |
1.09 |
0.93 to 1.27 |
0.28 |
| Coma on ICU admission |
-0.83 |
0.44 |
0.19 to 1.03 |
0.06 |
| ARDS before VAP |
0.52 |
1.69 |
0.86 to 3.31 |
0.13 |
| RRT before VAP |
-0.42 |
0.66 |
0.31 to 1.42 |
0.29 |
| Duration of hospitalisation before VAP |
0.006 |
1.01 |
1.00 to 1.02 |
0.20 |
| One antibiotic before VAP |
0.06 |
1.06 |
0.39 to 2.92 |
0.90 |
| Two antibiotic classes before VAP |
0.85 |
2.34 |
0.82 to 6.71 |
0.11 |
| More than two antibiotic classes before VAP |
1.37 |
3.93 |
1.26 to 12.23 |
0.02 |
| Constant |
-2.72 |
|||
| Backward stepwise |
||||
| Coma on ICU admission |
-1.12 |
0.32 |
0.14 to 0.73 |
0.01 |
| Two antibiotic classes before VAP |
0.88 |
2.41 |
1.22 to 4.79 |
0.01 |
| More than two antibiotic classes before VAP |
1.50 |
4.47 |
2.15 to 9.31 |
< 0.001 |
| Constant |
-1.50 |
|||
|
Overall correct prediction: 77%. Hosmer-Lemeshow goodness-of-fit: Chi-square 4.74, p = 0.8, eight degrees of freedom. ROC curve: area under the curve = 0.80 (0.73 to 0.86). ARDS = acute respiratory distress syndrome; CI = confidence interval; ICU = intensive care unit; MDR = multidrug resistant; OR = odds ratio; RRT = renal replacement therapy; VAP = ventilator-associated pneumonia. | ||||
Depuydt et al. Critical Care 2008 12:R142 doi:10.1186/cc7119 |
||||