|
Global oxygen transport variables and acid-base balance of study patients |
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| Baseline |
12 hours |
P value |
|
|
|
|||
| Oxygen delivery index (ml/min/m2) |
0.951 |
||
| Phenylephrine |
500 ± 205 |
498 ± 177 |
|
| Norepinephrine |
499 ± 139 |
506 ± 140 |
|
| Oxygen consumption index (ml/min/m2) |
0.568 |
||
| Phenylephrine |
164 ± 48 |
150 ± 41 |
|
| Norepinephrine |
173 ± 53 |
161 ± 58 |
|
| Oxygen extraction ratio (%) |
0.816 |
||
| Phenylephrine |
34 ± 9 |
32 ± 8 |
|
| Norepinephrine |
36 ± 11 |
32 ± 10* |
|
| Hemoglobin (g/dl) |
0.699 |
||
| Phenylephrine |
8.4 ± 0.9 |
8.4 ± 1.1 |
|
| Norepinephrine |
8.3 ± 0.7 |
8.4 ± 0.6 |
|
| pHa (-log10c(H+)) |
0.435 |
||
| Phenylephrine |
7.37 ± 0.07 |
7.37 ± 0.08 |
|
| Norepinephrine |
7.35 ± 0.09 |
7.34 ± 0.08 |
|
| Arterial base excess (mmol/l) |
0.228 |
||
| Phenylephrine |
-0.2 ± 5.8 |
0.2 ± 6.3 |
|
| Norepinephrine |
-2.4 ± 6.6 |
-3.0 ± 6.4 |
|
| Arterial carbon dioxide partial pressure (mmHg) |
0.346 |
||
| Phenylephrine |
44 ± 10 |
44 ± 10 |
|
| Norepinephrine |
41 ± 6 |
41 ± 6 |
|
| Arterial oxygen partial pressure (mmHg) |
0.963 |
||
| Phenylephrine |
128 ± 36 |
119 ± 31 |
|
| Norepinephrine |
121 ± 24 |
120 ± 26 |
|
| Arterial oxygen saturation (%) |
0.912 |
||
| Phenylephrine |
98 ± 2 |
98 ± 2 |
|
| Norepinephrine |
98 ± 1 |
98 ± 2 |
|
| Mixed venous oxygen saturation (%) |
0.431 |
||
| Phenylephrine |
66 ± 9 |
67 ± 9 |
|
| Norepinephrine |
64 ± 11 |
67 ± 10 |
|
| PaO2/FiO2 |
0.971 |
||
| Phenylephrine |
229 ± 103 |
208 ± 89 |
|
| Norepinephrine |
222 ± 75 |
218 ± 71 |
|
|
PaO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction (Horovitz index). *P < 0.05 versus baseline (significant time effect). | |||
Morelli et al. Critical Care 2008 12:R143 doi:10.1186/cc7121 |
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