Table 2

Characteristics and outcome depending on degree of renal function.

No AKI
n = 14,405
(65.6%)
 AKI 1
n = 4259
(19.1%)
 AKI II
n = 857
(3.8%)
 AKI III
n = 2782
(12.5%)
 AKI
(I + II + III)
n = 7898
(35.4%)
 p
AKI
vs no AKI
 p
AKI III
vs
AKI I
Age
Mean (SD)
 60.5 (16.56)
 62.1 (15.93)
 60.4 (16.55)
 61.1 (15.66)
 61.5 (15.91)
 < 0.0001
 0.089
Range
 16 to 99
 16 to 95
 16 to 92
 16 to 90
 16 to 95

APACHE II score at admission to ICU
Median
 13
 16
 17
 21
 18
 < 0.0001
 < 0.0001
Range
 0 to 49
 0 to 44
 3 to 39
 1 to 52
 0 to 52

SOFA score on admission to ICU
Median
 5
 7
 7
 9
 7
 < 0.0001
 < 0.0001
Range
 0 to 21
 0 to 18
 2 to 19
 0 to 22
 0 to 22

Number of associated failed organs at admission to ICU*
Median
 0
 1
 1
 1
 1
 < 0.0001
 < 0.0001
Range
 0 to 6
 0 to 5
 0 to 5
 0 to 6
 0 to 6

Maximum number of associated failed organ systems*
Median
 1
 1
 2
 2
 2
 < 0.0001
 < 0.0001
Range
 0 to 6
 0 to 5
 0 to 6
 0 to 6
 0 to 6

Mechanical ventilation
Number of patients
 8379 (58.2%)
 3441
(80.8%)
 696
(81.2%)
 2416
(86.8%)
 6553
(82.97%)
 < 0.0001
 < 0.0001
Outcome
ICU
mortality
 1548
(10.7%)
 856
(20.1%)
 222
(25.9%)
 1379
(49.6%)
 2457
(31.1%)
 < 0.0001
 < 0.0001
Hospital
mortality
 2438
(16.9%)
 1272
(29.9%)
 307
(35.8%)
 1610
(57.9%)
 3189
(40.4%)
 < 0.0001
 < 0.0001
Length of stay in ICU (days): ICU survivors
Median
 2
 6
 7
 9
 7
 < 0.0001
 < 0.0001
Range
 (2 to 55)
 (3 to 109)
 (3 to 112)
 (1 to 270)
 (1 to 270)

Length of stay in ICU (days): ICU non-survivors
Median
 2
 7
 7
 8
 7
 < 0.0001
 < 0.0001
Range
 (2 to 64)
 (3 to 73)
 (3 to 54)
 (1 to 110)
 (1 to 110)

Timing of AKI in ICU
First 48 hours
 -
 3529 (82.9%)
 558 (65.1%)
 2075 (74.6%)
 6162 (78.0%)

Day 3 to 5
 -
 424 (9.96%)
 120 (14.0%)
 332 (11.9%)
 876 (11.1%)

Day 6 to 9
 -
 193 (4.5%)
 68 (7.9%)
 207 (7.4%)
 468 (5.9%)

Day 10 – 14
 -
 73
(1.7%)
 49
(5.7%)
 99
(3.6%)
 221
(2.8%)

Day 15 – 19
 -
 20
(0.5%)
 20
(2.3%)
 31
(1.1%)
 71
(0.9%)

> 19th day
 -
 20
(0.5%)
 42
(4.9%)
 38
(1.4%)
 100
(1.3%)

* excluding acute kidney injury

AKI = acute kidney injury; APACHE = Acute Physiology and Chronic Health Evaluation; ICU = intensive care unit; SD = standard deviation; SOFA score = Sequential Organ Failure Assessment score.

Ostermann et al. Critical Care 2008 12:R144   doi:10.1186/cc7123