Table 6

Progression of AKI/

AKI progression

Number of patients

ICU mortality

p

AKI I (n = 4259)

with rising creatinine values

1995 (46.8%)

522 (26.2%)

< 0.0001

with falling creatinine values

2264 (53.2%)

334 (14.8%)

AKI II (n = 857)

with rising creatinine values

439 (51.2%)

157 (35.8%)

< 0.0001

with falling creatinine values

418 (48.8%)

65 (15.6%)

AKI III (n = 2782)

with rising creatinine values

639 (23%)

318 (49.8%)

< 0.0001

with falling creatinine values

296 (10.6%)

62 (20.9%)

AKI III based on RRT criteria

1847 (66.4%)

999 (54.1%)

AKI I/AKI II progressing to AKI III

1664 (59.8%)

796 (47.8%)

p = 0.029

AKI III without prior AKI I/AKI II

1118 (40.2%)

583 (46.2%)

AKI = acute kidney injury; ICU = intensive care unit; RRT = renal replacement therapy.

Ostermann et al. Critical Care 2008 12:R144   doi:10.1186/cc7123