Table 6

Progression of AKI/

AKI progression
Number of patients
ICU mortality
p

AKI I (n = 4259)



with rising creatinine values
1995 (46.8%)
522 (26.2%)
< 0.0001
with falling creatinine values
2264 (53.2%)
334 (14.8%)

AKI II (n = 857)



with rising creatinine values
439 (51.2%)
157 (35.8%)
< 0.0001
with falling creatinine values
418 (48.8%)
65 (15.6%)

AKI III (n = 2782)



with rising creatinine values
639 (23%)
318 (49.8%)
< 0.0001
with falling creatinine values
296 (10.6%)
62 (20.9%)

AKI III based on RRT criteria
1847 (66.4%)
999 (54.1%)

AKI I/AKI II progressing to AKI III
1664 (59.8%)
796 (47.8%)
p = 0.029
AKI III without prior AKI I/AKI II
1118 (40.2%)
583 (46.2%)


AKI = acute kidney injury; ICU = intensive care unit; RRT = renal replacement therapy.

Ostermann et al. Critical Care 2008 12:R144   doi:10.1186/cc7123