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Data on the study patients by subgroup |
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| Parameter |
Normal lung function (group N) |
Primary lung disorder (group P) |
Secondary lung disorder (group S) |
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| n |
19 |
16 |
10 |
|
|
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| Female sex (%) |
36.8 |
31.3 |
30.0 |
|
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| Age (years) |
49 ± 16 |
52 ± 17 |
52 ± 18 |
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| Height (cm) |
176 ± 9 |
177 ± 10 |
169 ± 6 |
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| Weight (kg) |
73.6 ± 11.6 |
76.4 ± 15.0 |
78.7 ± 27.3 |
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| PBW (kg) |
69.8 ± 10.6 |
71.0 ± 10.8 |
64.4 ± 7.2 |
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| LIS |
0.9 ± 0.5 |
2.4 ± 0.8 |
2.1 ± 0.3 |
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| Tint (hours) |
20.2 ± 16.6 |
28.9 ± 46.9 |
30.1 ± 26.2 |
|
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| Survival (n/n [%]) |
16/19 (84%) |
13/16 (81%) |
4/10 (40%) |
|
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| Baseline PEEP (cmH2O) |
6.2 ± 2.1 |
11.3 ± 4.1** |
11.1 ± 2.6** |
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| Baseline Pao2/Fio2 ratio (kPa) |
49.7 ± 11.9 |
26.1 ± 11.2** |
32.7 ± 13.1* |
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| Baseline compliance dynamic (ml/cmH2O) |
50.3 ± 13.0 |
35.6 ± 12.1* |
38.8 ± 12.2* |
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| Predicted sitting EELV (l) |
3.3 ± 0.4 |
3.4 ± 0.4 |
3.2 ± 0.2 |
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| Ventilation mode |
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| Pressure control |
7 |
8 |
4 |
|
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| Pressure support |
5 |
6 |
6 |
|
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| Volume control |
1 |
0 |
0 |
|
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| Pressure controlled – volume guaranteed |
6 |
2 |
0 |
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Unless otherwise stated, values are presented as mean ± standard deviation. The LIS (Murray) is based on dynamic compliance. *P = 0.05, **P = 0.001, versus group N. LIS, Lung Injury Score; PBW, predicted body weight; PEEP, positive end-expiratory pressure; Tint, time between intubation and inclusion. | |||
Bikker et al. Critical Care 2008 12:R145 doi:10.1186/cc7125 |
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