Figure 2.

Changes in arterial oxygen partial pressure (PaO₂) and mixed venous oxygen saturation (SvO₂) in awake instrumented sheep subjected to intravenous bolus injection of oleic acid (OA) and co-administration of recombinant human activated protein C (rhAPC). In the figure, OA refers to the oleic acid-alone group (n = 8), OA+rhAPC refers to the rhAPC-treated OA group (n = 8), and sham refers to sham-operated animals (n = 6). Data are presented as mean ± standard error of the mean. *P < 0.05 between OA and OA+rhAPC groups; ^†P < 0.05 from t = 0 hours in the OA group.