Table 4 |
||||
|
Perioperative data |
||||
|
Group |
Subgroup |
Control |
Insulin |
p Value |
|
|
||||
|
Study interval |
August to December 2004 |
June 2005 to June 2006 |
||
|
Procedure, n (%): |
CABG |
97 (31.8) |
218 (29.3) |
0.41 |
|
Valve |
132 (43.3) |
291 (39.0) |
0.21 |
|
|
Combined |
76 (24.9) |
236 (31.7) |
0.03 |
|
|
Redo |
43 (14.2) |
104 (13.9) |
1.0 |
|
|
Emergency |
33 (10.9) |
61 (8.2) |
0.19 |
|
|
ICU length of stay (days), median (min-max) |
2 (1 to 73) |
2 (1 to 106) |
0.61 |
|
|
Aprotinin usage, n (%) |
29 (9.5) |
103 (13.8) |
0.06 |
|
|
Administration of intravenous diuretics into the ICU, n(%) |
50 (16.4) |
121 (16.2) |
1.0 |
|
|
Patients with packed cell transfusion, n (%) |
240 (78.7) |
524 (70.3) |
0.006 |
|
|
Packed cells per patient, median (min-max) |
2 (0 to 18) |
2 (0 to 19) |
0.66 |
|
|
Blood glucose level (mg/dL): |
Induction |
109 ± 39 |
104 ± 24 |
0.20 |
|
End of surgery |
115 ± 25 |
108 ± 22 |
< 0.001 |
|
|
Admission to ICU |
118 ± 29 |
107 ± 22 |
< 0.001 |
|
|
Mean in the ICU |
133 ± 29 |
103 ± 15 |
< 0.0001 |
|
|
Serum creatinine levels (g/dL): |
||||
|
Non-diabetics |
Preoperative |
1.0 ± 0.7 |
1.0 ± 0.5 |
0.99 |
|
Max in the ICU |
1.3 ± 1.0 |
1.1 ± 0.6 |
0.09 |
|
|
Max post ICU |
1.0 ± 1.0 |
0.9 ± 0.8 |
0.33 |
|
|
Diabetics |
Preoperative |
1.0 ± 0.3 |
1.2 ± 1.1 |
0.11 |
|
Max in the ICU |
1.3 ± 1.2 |
1.4 ± 1.0 |
0.31 |
|
|
Max post ICU |
1.2 ± 1.7 |
1.3 ± 1.4 |
0.57 |
|
|
Morbidity, n (%): |
||||
|
Non-diabetics |
Cardiac |
56 (24.0) |
62 (10.6) |
< 0.0001 |
|
Renal |
9 (3.9) |
4 (0.7) |
< 0.01 |
|
|
Pulmonary |
7 (3.0) |
38 (6.5) |
0.06 |
|
|
Infectious |
23 (9.9) |
25 (4.3) |
< 0.01 |
|
|
Other |
9 (3.9) |
24 (4.1) |
1.0 |
|
|
Diabetics |
Cardiac |
22 (31.4) |
46 (28.4) |
0.64 |
|
Renal |
4 (5.7) |
5 (3.1) |
0.45 |
|
|
Pulmonary |
6 (8.6) |
15 (9.3) |
1.0 |
|
|
Infectious |
5 (7.1) |
7 (4.3) |
0.35 |
|
|
Other |
2 (2.9) |
8 (4.9) |
0.72 |
|
|
30-day Mortality, n (%): |
||||
|
Non-diabetics |
7 (3.0) |
5 (0.9) |
< 0.05 |
|
|
Diabetics |
4 (5.6) |
4 (2.5) |
0.25 |
|
|
Cause of death, n (%): |
||||
|
Cardiac |
4 (36.4) |
2 (22.2) |
0.64 |
|
|
Respiratory |
0 (0.0) |
1 (11.1) |
0.45 |
|
|
Sepsis |
1 (9.1) |
1 (11.1) |
1.0 |
|
|
Multi organ failure |
5 (45.4) |
4 (44.4) |
1.0 |
|
|
Other |
1 (9.1) |
1 (11.1) |
1.0 |
|
|
|
||||
|
Data are presented as mean ± SD or number (%) unless otherwise mentioned. CABG, coronary artery bypass graft; ICU, Intensive Care Unit; SD, standard deviation. |
||||
|
Lecomte et al. Critical Care 2008 12:R154 doi:10.1186/cc7145 |
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