Table 2 |
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|
Renal haemodynamics, oxygen exchange and acid base balance |
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|
Group |
Baseline |
12 hours |
18 hours |
22 hours |
|
|
|
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|
Delta creatinine |
Control |
0 (0 to 0) |
-1.5 (-7 to 0) |
0.5 (-4 to 11) |
2 (-1 to 11) |
|
(μmol/l) |
AKI |
0 (0 to 0) |
8 (-12 to 27) |
23 (-3 to 46) |
31 (18 to 60)*§ |
|
|
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|
RBF |
Control |
5 (5 to 9) |
4 (4 to 6) |
4 (3 to 6) |
4 (3 to 6) |
|
(ml/kg) |
AKI |
6 (4 to 8) |
5 (4 to 8) |
7 (5 to 7) |
4 (3 to 4)* |
|
|
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|
RVP |
Control |
9 (8 to 10) |
15 (12 to 16) |
13 (12 to 14) |
12 (11 to 20) |
|
(mmHg) |
AKI |
13 (11 to 15) |
14 (12 to 16) |
16 (15 to 19)*§ |
21 (18 to 25)* |
|
|
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|
RPP |
Control |
82 (77 to 89) |
68 (59 to 72) |
65 (58 to 70) |
70 (44 to 75) |
|
(mmHg) |
AKI |
84 (76 to 87) |
71 (59 to 78)* |
63 (55 to 65)* |
51 (48 to 58)* |
|
|
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|
Renal DO2 |
Control |
0.63 (0.55 to 0.93) |
0.48 (0.42 to 0.68) |
0.47 (0.39 to 0.70) |
0.40 (0.34 to 0.63) |
|
(ml/min/kg) |
AKI |
0.81 (0.59 to 0.97) |
0.87 (0.46 to 1.16) |
0.8 (0.53 to 0.87) |
0.50 (0.22 to 0.58) |
|
|
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|
Renal VO2 |
Control |
0.17 (0.13 to 0.22) |
0.14 (0.13 to 0,24) |
0.18 (0.13 to 0.21) |
0.19 (0.14 to 0.22) |
|
(ml/min/kg) |
AKI |
0.21 (0.14 to 0.24) |
0.17 (0.08 to 0.23) |
0.23 (0.21 to 0.23) |
0.17 (0.12 to 0.24) |
|
|
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|
Renal ER |
Control |
28 (22 to 33) |
33 (31 to 39) |
33 (31 to 39) |
32 (30 to 52) |
|
(%) |
AKI |
26 (22 to 27) |
26 (16 to 32) |
25 (21 to 45) |
37 (34 to 58)* |
|
|
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|
Renal venous pH |
Control |
7.54 (7.53 to 7.55) |
7.5 (7.48 to 7.53) |
7.53 (7.51 to 7.56) |
7.50 (7.47 to 7.57) |
|
AKI |
7.53 (7.5 to 7.57) |
7.42 (7.42 to 7.47)*§ |
7.4 (7.21 to 7.47)*§ |
7.31 (7.01 to 7.35) § |
|
|
|
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|
UO |
Control |
4 (3 to 6) |
3 (2 to 6) |
4 (3 to 6) |
4 (3 to 5) |
|
(ml/kg/h) |
AKI |
2 (2 to 3)§ |
2 (1 to 4) |
2 (1 to 2)§ |
1 (1 to 2)*§ |
|
|
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|
DO2 = oxygen delivery, ER = extraction ratio, RBF = renal blood flow, RPP = renal perfusion pressure, RVP = renal venous pressure, UO = urine output, VO2 = oxygen uptake. Control = sham operated group; AKI = peritonitis induced group * significant difference within each group vs. baseline (p < 0.05); §significant diference between groups (p < 0.05) Data are median and 25th and 75th quartiles. |
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|
Chvojka et al. Critical Care 2008 12:R164 doi:10.1186/cc7164 |
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